67219-54-9

Upstream product

• 4318-05-2 2-(acetylamino)-9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 4318-06-3 N²-acetyldeoxyguanosine 

Downstream Products

• 175400-28-9 5'-O-dimethoxytrityl-3'-O-(tert-butyldimethylsilyl)-N²-acetyldeoxyguanosine 
• 175400-30-3 O⁶<2-methoxy-6-chloro-9-(ω-pentylamino)>-acridine-5'-O-dimethoxytrityl-3'-O-(tert-butyldimethylsilyl)-N²-acetyldeoxyguanosine 
• 175400-29-0 O⁶-(2,4,6-triisopropylbenzenesulfonyl)-5'-O-dimethoxytrityl-3'-O-(tert-butyldimethylsilyl)-N²-acetyldeoxyguanosine 
• 175400-31-4 O⁶<2-methoxy-6-chloro-9-(ω-pentylamino)>-acridine-5'-O-dimethoxytrityl-N²-acetyldeoxyguanosine 

Relevant academic research and scientific papers

Synthesis and characterization of O6-modified deoxyguanosine-containing oligodeoxyribonucleotides for triple-helix formation

Two new modified deoxyguanosine derivatives linked through their C-6 position to a psoralen and an acridine derivative have been synthesized and incorporated into oligonucleotide chains. Difficulties observed during the purification of oligonucleotides containing a stretch of G and one method used to solve this problem are discussed.