672307-83-4

Basic information

• Product Name: 5-Pyrimidinecarboxaldehyde, 2-(methylamino)- (9CI)
• Synonyms: 5-Pyrimidinecarboxaldehyde, 2-(methylamino)- (9CI)
• CAS NO: 672307-83-4
• Molecular Formula: C₆H₇N₃O
• Molecular Weight: 137.13928
• Product Categories: PYRIMIDINE
• Mol File: 672307-83-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 305.4±34.0 °C(Predicted)
• Appearance: /
• Density: 1.281±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.13±0.10(Predicted)
• CAS DataBase Reference: 5-Pyrimidinecarboxaldehyde, 2-(methylamino)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxaldehyde, 2-(methylamino)- (9CI)(672307-83-4)
• EPA Substance Registry System: 5-Pyrimidinecarboxaldehyde, 2-(methylamino)- (9CI)(672307-83-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 672307-83-4(Hazardous Substances Data)

Usage

Uses

2-Methylamino-pyrimidine-5-carbaldehyde can be prepared to use as ATM inhibitors for therapeutic agents and anti-cancer drug sensitivity enhancers.

Downstream Products

• 1620092-97-8 (E)-5-(2,6-dichlorostyryl)-2-(N-methylamino)pyrimidine 
• 1620092-95-6 (E)-5-(2-chloro-6-fluorostyryl)-2-(N-methylamino)-pyrimidine 
• 1620092-92-3 (E)-5-(2,6-difluorostyryl)-2-(N-methylamino)pyrimidine 

Relevant articles and documents

PYRAZOLOPYRIMIDINES AS CYCLIN-DEPENDENT KINASE INHIBITORS

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.