672309-94-3 Usage
Uses
Used in Pharmaceutical Industry:
(R)-2-CBZ-AMINO-BUTANE-1,4-DIOL is used as a chiral building block for the synthesis of enantiomerically pure compounds. Its application is crucial in the development of drugs with specific biological activities, ensuring the desired therapeutic effects and minimizing potential side effects associated with impurities or racemic mixtures.
Used in Chemical Synthesis:
In the realm of chemical synthesis, (R)-2-CBZ-AMINO-BUTANE-1,4-DIOL is utilized as a reagent to create a variety of organic molecules with precise stereochemistry. This is particularly important in the synthesis of complex molecules where the spatial arrangement of atoms can significantly influence the molecule's properties and reactivity.
Used in Peptide Synthesis:
(R)-2-CBZ-AMINO-BUTANE-1,4-DIOL is employed as a key component in peptide synthesis, allowing for the controlled assembly of amino acids into specific sequences. The protection of the amino group by the carbamate group (CBZ) facilitates the stepwise construction of peptide chains, which can be later deprotected to yield the desired peptide product.
Overall, (R)-2-CBZ-AMINO-BUTANE-1,4-DIOL's versatility in chemical synthesis and its role in producing enantiomerically pure compounds make it an indispensable tool in both pharmaceutical and chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 672309-94-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,3,0 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 672309-94:
(8*6)+(7*7)+(6*2)+(5*3)+(4*0)+(3*9)+(2*9)+(1*4)=173
173 % 10 = 3
So 672309-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO4/c14-7-6-11(8-15)13-12(16)17-9-10-4-2-1-3-5-10/h1-5,11,14-15H,6-9H2,(H,13,16)/t11-/m1/s1
672309-94-3Relevant academic research and scientific papers
Preparation method of ceftobiprole intermediate (R)-1-benzyl-3-aminopyrrolidine
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, (2020/09/16)
The invention discloses a preparation method of a ceftobiprole intermediate, namely (R)-1-benzyl-3-aminopyrrolidine. The preparation method specifically comprises the following steps: with D-asparticacid as an initial raw material, carrying out amino protection, esterification, reduction, bromination cyclization and 3-amino protection removal successively to obtain (R)-1-benzyl-3-aminopyrrolidine. According to the method, the defects that raw materials for preparing (R)-1-benzyl-3-aminopyrrolidine are expensive, high temperature and high pressure are needed, precious metal is used for catalysis and the like in the prior art are overcome. All the materials used in the invention are cheap and easily available, so cost is low; and reactions can be carried out at normal temperature, so energyconsumption is low, industrial production is facilitated, and pollution is small.
A kind of optical active pharmaceutical process for the preparation of intermediates
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Paragraph 0054; 0055, (2016/10/17)
The invention relates to a preparation method of an optical active compound, represented by formula I, or a hydrochloride of the optical active compound by taking a compound with optical activity as a starting material. Raw materials of the preparation method are cheap and easily available; no splitting is needed; the whole technological operation is simple and convenient; cost is low; pollution on environment is less; and the preparation method is suitable for industrialized production. In the formula I, n is 1 or 2 or 3.
