67259-45-4Relevant academic research and scientific papers
Synthesis of Some 2-Amino-4-phenyl-3H-1,5-benzodiazepines by Reaction of Aromatic Diamines and Acetylenic Imidates
Unangst, Paul C.
, p. 1257 - 1260 (2007/10/02)
The reaction of several aromatic 1,2-diamines with conjugated acetylenic imidate salts is described.The use of hexamethylphosphoric triamide (HMPA) as the solvent allows preparation of 2-amino-4-phenyl-3H-1,5-benzodiazepines in a one-step reaction.
Synthesis and biological evaluation of some 2-amino-4-aryl-3H-1,5-benzodiazepine analogues of clozapine
Ellefson,Woo,Miller,Kehr
, p. 952 - 957 (2007/10/05)
2-Amino-4-aryl-3H-1,5-benzodiazepines were prepared and evaluated for potential neuroleptic activity. One compound showed some activity in the four assays; however, the activity was not consistently observed among other members of the series. The data ref
