67273-43-2 Usage
Structure
Benzimidazole derivative with a pyridine group attached to the benzimidazole ring
Classification
Proton pump inhibitor
Use
Treatment of conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers
Mechanism of action
Selective and irreversible inhibition of the H+/K+ ATPase enzyme system responsible for acid production in the stomach
Effect
Alleviation of symptoms associated with excessive stomach acid
Check Digit Verification of cas no
The CAS Registry Mumber 67273-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,7 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67273-43:
(7*6)+(6*7)+(5*2)+(4*7)+(3*3)+(2*4)+(1*3)=142
142 % 10 = 2
So 67273-43-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H13N3/c1-2-10-7-8-13(15-9-10)14-16-11-5-3-4-6-12(11)17-14/h3-9H,2H2,1H3,(H,16,17)
67273-43-2Relevant articles and documents
Synthesis of a group of 1H-benzimidazoles and their screening for antiinflammatory activity
Evans,Hicks,Williamson,Dawson,Meacock,Kitchen
, p. 635 - 642 (2007/10/03)
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2-Substituted benzimidazole compounds
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, (2008/06/13)
2-Substituted benzimidazole compounds of the formula: STR1 wherein R 1 is hydrogen, halogen, lower alkyl or lower alkoxy, and R 2 is hydrogen or lower alkyl with the proviso that R 1 and R 2 do not stand for hydrogen simultaneously and, when R 1 is hydrogen, R 2 cannot mean a methyl group at the 6th position on the pyridin-2-yl group or methyl an isobutyl group on the phenyl group; are useful as anti-inflammatory agents and/or analgesics.
