67273-59-0

Usage

Class

Proton pump inhibitors (PPIs)

Primary Use

Treatment of stomach and esophagus problems (such as acid reflux, ulcers, and gastroesophageal reflux disease (GERD))

Mechanism of Action

Reduces the amount of acid produced in the stomach

Prescription

Commonly prescribed for short-term treatment and long-term management

Available Forms

Capsules, tablets, and powder for oral suspension

Side Effects

Nausea, diarrhea, and headaches (among others)

Long-Term Risks

Increased risk of bone fractures and low magnesium levels

Upstream product

• 34136-57-7 m-ethylbenzonitrile 
• 95-54-5 1,2-diamino-benzene 

Relevant academic research and scientific papers

Microwave use of amidine compounds in the aqueous phase benzoate synthesis of benzimidazole compounds method

The invention discloses a microwave the use of amidine compounds in the aqueous phase benzoate synthesis of benzimidazole compounds, in the aqueous phase under microwave conditions adding benzoic amidine compound under alkaline condition [...] into benzimidazole reaction, invention an environment-friendly, the operation is simple, cheap and safe, efficient process for preparing benzimidazole method. Compared with the prior art, this method not only can be applied to a large number of functional groups, the productive rate is high, few by-products, and the operation is simple, safe, low cost, environmental protection; .

Method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions

The invention discloses a method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions. According to the method, glacial aceticacid is taken as a catalyst; at solvent-free room temperature conditions, physical grinding is adopted, reaction of 2-substituted arylamines (2-mercapto arylamine, 2-aminophenol, and o-phenylenediamine) and aromatic aldehydes is carried out using physical grinding. The method is friendly to the environment, is simple in operation, is safe, is low in cost, and is high in efficiency. Compared withthe prior art, the advantages are that: the method is suitable for a large amount of functional groups, yield is high, less by-product is generated, operation is simple, the method is safe, cost is low, and the method is friendly to the environment.

Method for catalytically synthesizing benzimidazole compound by organic protonic acid under condition of no solvent

The invention discloses a method for catalytically synthesizing a benzimidazole compound by organic protonic acid under the condition of no solvent. According to the method provided by the invention,high efficiency catalysis is carried out to rapidly prep

2-Substituted benzimidazole compounds

2-Substituted benzimidazole compounds of the formula: STR1 wherein R 1 is hydrogen, halogen, lower alkyl or lower alkoxy, and R 2 is hydrogen or lower alkyl with the proviso that R 1 and R 2 do not stand for hydrogen simultaneously and, when R 1 is hydrogen, R 2 cannot mean a methyl group at the 6th position on the pyridin-2-yl group or methyl an isobutyl group on the phenyl group; are useful as anti-inflammatory agents and/or analgesics.