67285-27-2Relevant academic research and scientific papers
Total Synthesis of Tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: Structure-Activity Relationship Studies against Drug-Resistant Bacteria
Huang, Jing-Kai,Yang Lauderdale, Tsai-Ling,Lin, Chun-Cheng,Shia, Kak-Shan
, p. 6508 - 6523 (2018)
Making use of a reductive olefin coupling reaction and Michael-Dieckmann condensation as two key operations, we have completed a concise total synthesis of tetarimycin A, (±)-naphthacemycin A9, and (±)-fasamycin A in a highly convergent and pra
Total synthesis and structural revision of viridicatumtoxin B
Nicolaou,Nilewski, Christian,Hale, Christopher R. H.,Ioannidou, Heraklidia A.,Elmarrouni, Abdelatif,Koch, Lizanne G.
, p. 8736 - 8741 (2013/09/12)
Will the real viridicatumtoxin B please stand up: The total synthesis of viridicatumtoxin B resulted in its structural revision and opens the way for analogue construction and biological evaluation of this complex tetracycline-like antibiotic. The highly convergent strategy employed allows for swift construction of the entire carbocyclic framework of the molecule. Copyright
Synthesis of 3-hydroxy-5-alkoxyhomophthalates by domino '2:1-coupling/intramolecular aldol condensation' reactions of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with tetraalkoxymethanes
Lubbe, Mathias,Langer, Peter
experimental part, p. 881 - 885 (2010/06/20)
The first domino '2:1 condensation/intramolecular aldol' reactions of 1,3-bis(trimethylsilyloxy)-1,3-butadiene with tetraalkoxymethanes provide a convenient approach to 3-hydroxy-5-alkoxyhomophthalates. These products, which contain one free and one protected hydroxyl group, can be functionalized by palladium(0)-catalyzed cross-coupling reactions. The Royal Society of Chemistry 2010.
