672906-68-2 Usage
Uses
Used in Pharmaceutical Industry:
(R)-N-METHYL-1-(4-FLUOROPHENYL)ETHYLAMINE is used as a precursor in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved properties, such as enhanced bioavailability and selectivity.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-N-METHYL-1-(4-FLUOROPHENYL)ETHYLAMINE is used as a building block for the creation of complex organic molecules, leveraging its unique structural features to achieve specific chemical reactions and outcomes.
Used in Medicinal Chemistry:
(R)-N-METHYL-1-(4-FLUOROPHENYL)ETHYLAMINE is employed in medicinal chemistry for the development of fluorinated compounds, which can possess altered pharmacokinetic and pharmacodynamic properties compared to their non-fluorinated counterparts, potentially leading to more effective therapeutic agents.
Used in Research and Development:
In research and development settings, (R)-N-METHYL-1-(4-FLUOROPHENYL)ETHYLAMINE serves as a valuable compound for studying the effects of stereochemistry on biological activity and for exploring the potential of fluorination in drug design.
Check Digit Verification of cas no
The CAS Registry Mumber 672906-68-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,9,0 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 672906-68:
(8*6)+(7*7)+(6*2)+(5*9)+(4*0)+(3*6)+(2*6)+(1*8)=192
192 % 10 = 2
So 672906-68-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H12FN/c1-7(11-2)8-3-5-9(10)6-4-8/h3-7,11H,1-2H3/t7-/m1/s1
672906-68-2Relevant academic research and scientific papers
Tackling N-Alkyl Imines with 3d Metal Catalysis: Highly Enantioselective Iron-Catalyzed Synthesis of α-Chiral Amines
Blasius, Clemens K.,Gade, Lutz H.,Heinrich, Niklas F.,Vasilenko, Vladislav
, p. 15974 - 15977 (2020/07/04)
A readily activated iron alkyl precatalyst effectively catalyzes the highly enantioselective hydroboration of N-alkyl imines. Employing a chiral bis(oxazolinylmethylidene)isoindoline pincer ligand, the asymmetric reduction of various acyclic N-alkyl imines provided the corresponding α-chiral amines in excellent yields and with up to >99 % ee. The applicability of this base metal catalytic system was further demonstrated with the synthesis of the pharmaceuticals Fendiline and Tecalcet.
OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME
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Page 32, (2010/02/06)
An optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative represented by the formula [4] is produced by a process including (a) reacting an optically active secondary amine, represented by th
