Basic information

Product Name: FURIN INHIBITOR II
Synonyms: HEXA-D-ARGININE;H-(D)RRRRRR-NH2;FURIN INHIBITOR II;H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;Hexa-D-arginine aMide
CAS NO:673202-67-0
Molecular Formula: C36H75N25O6
Molecular Weight: 954.14
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: 1.59±0.1 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: -20°C
Solubility: N/A
PKA: 13.24±0.46(Predicted)
CAS DataBase Reference: FURIN INHIBITOR II(CAS DataBase Reference)
NIST Chemistry Reference: FURIN INHIBITOR II(673202-67-0)
EPA Substance Registry System: FURIN INHIBITOR II(673202-67-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 673202-67-0(Hazardous Substances Data)

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SDS
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673202-67-0 Usage

Uses

Used in Cellular and Molecular Research:
FURIN INHIBITOR II is used as a research tool for studying the effects of furin inhibition on various cellular processes. It helps researchers understand the role of furin in protein processing and its impact on cell signaling and function.
Used in the Study of TGF-β1 Induced GDNF Production:
FURIN INHIBITOR II is used as an inhibitor to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG). This application aids in understanding the role of furin in TGF-β1 signaling and its influence on GDNF production.
Used in the Study of (Pro) Renin Receptor Cleavage:
FURIN INHIBITOR II is used as an inhibitor to study its effect on the cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells. This application helps researchers investigate the role of furin in the regulation of (Pro) renin receptor processing and its implications in kidney function.
Used in Furin Cleavage Assays:
FURIN INHIBITOR II is used as a specific inhibitor in furin cleavage assays, allowing researchers to assess the activity of furin in various experimental setups. This application is essential for understanding the role of furin in protein processing and its potential as a therapeutic target in various diseases.

Biochem/physiol Actions

Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).

Check Digit Verification of cas no

The CAS Registry Mumber 673202-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,3,2,0 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 673202-67:
(8*6)+(7*7)+(6*3)+(5*2)+(4*0)+(3*2)+(2*6)+(1*7)=150
150 % 10 = 0
So 673202-67-0 is a valid CAS Registry Number.

673202-67-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	hexa-D-arginine

1.2 Other means of identification

Product number	-
Other names	FURIN INHIBITOR II

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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