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Ufenamate, also known as Butyl flufenamate, is a topical, non-steroidal anti-inflammatory agent with light yellow liquid properties. It is indicated for the treatment of various skin conditions, including acute and chronic eczema, contact, seborrheic, and atopic dermatitis, as well as herpes zoster. Its chemical properties and brand names, such as FENAZOLE and COMBEC, contribute to its effectiveness in managing skin inflammation and discomfort.

67330-25-0

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Basic information
1. Product Name: ufenamate
2. Synonyms: ufenamate;BUTYL FLUFENAMATE;2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid butyl ester;Butyl fulfenamate;HF-264;o-(m-Trifluoromethylanilino)benzoic acid butyl ester;Combec;Fenazol
3. CAS NO:67330-25-0
4. Molecular Formula: C₁₈H₁₈F₃NO₂
5. Molecular Weight: 337.37
6. EINECS: N/A
7. Product Categories: Pharmaceutical Intermediates
8. Mol File: 67330-25-0.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 170°C/1mmHg(lit.)
3. Flash Point: 192.2oC
4. Appearance: /
5. Density: 1.2230 (estimate)
6. Vapor Pressure: 2.01E-06mmHg at 25°C
7. Refractive Index: 1.5530 to 1.5570
8. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
9. Solubility: N/A
10. PKA: -2.36±0.50(Predicted)
11. Merck: 14,4132
12. CAS DataBase Reference: ufenamate(CAS DataBase Reference)
13. NIST Chemistry Reference: ufenamate(67330-25-0)
14. EPA Substance Registry System: ufenamate(67330-25-0)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS: DH8511000
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 67330-25-0(Hazardous Substances Data)

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67330-25-0 Usage

Uses

Used in Dermatology:
Ufenamate is used as an ointment for the treatment of facial hormone-dependent dermatitis, cephalic chronic eczema, and neurodermatitis. It provides relief from inflammation and itching associated with these skin conditions, offering a non-steroidal alternative for managing symptoms.
Used in Pharmaceutical Industry:
Ufenamate is used as a non-steroidal anti-inflammatory agent for the treatment of various skin conditions, such as acute and chronic eczema, contact, seborrheic, and atopic dermatitis, and herpes zoster. Its light yellow liquid form and brand names like FENAZOLE and COMBEC make it a popular choice for pharmaceutical formulations targeting skin inflammation and related discomfort.

Originator

Hokaariku (Japan)

Check Digit Verification of cas no

The CAS Registry Mumber 67330-25-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,3,3 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 67330-25:
(7*6)+(6*7)+(5*3)+(4*3)+(3*0)+(2*2)+(1*5)=120
120 % 10 = 0
So 67330-25-0 is a valid CAS Registry Number.

InChI:InChI=1/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3