67337-74-0

Usage

Uses

Used in Chemical Synthesis:
2,4-Imidazolidinedione, 5-(hydroxymethyl)(9CI) is used as a reagent in organic chemistry reactions for the synthesis of other chemical compounds. Its unique structural properties contribute to the creation of a wide range of products.
Used in Pharmaceutical Industry:
2,4-Imidazolidinedione, 5-(hydroxymethyl)(9CI) is used as a building block in the development of pharmaceuticals. Its chemical reactivity and structural properties make it a valuable component in the formulation of new drugs.
Used in Agrochemical Industry:
2,4-Imidazolidinedione, 5-(hydroxymethyl)(9CI) is used as a component in the production of agrochemicals. Its properties allow for the creation of effective products for agricultural applications.
Used in Research and Development:
2,4-Imidazolidinedione, 5-(hydroxymethyl)(9CI) is used as a subject of study in research and development for its unique properties and chemical reactivity. This helps in understanding its potential applications and further advancements in various industries.

Upstream product

• 857766-66-6 5-chloromethyl-imidazolidine-2,4-dione 
• 302-84-1 serin 
• 30406-21-4 N-carbamyl-DL-serine 

Relevant academic research and scientific papers

Synthesis and reactivity of 5-methylenehydantoins

5-Methylenehydantoin, as well as the N-mono- and N,N-di-protected derivatives, can be obtained by different synthetic routes. These compounds can undergo a large variety of reactions, such as Diels-Alder, epoxidation, methanol addition and conjugate addition reactions of different types of nucleophiles, including carbon (cyanide), nitrogen (piperidine) and sulfur (thiols, thioacetate) nucleophiles. The reactivity with electrophilic reagents, such as m-CPBA or methanol in acidic medium, and the need for Lewis acids to promote the conjugate addition reactions indicate that hydantoin is a poor electron-withdrawing group.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

Synthesis of carbocyclic hydantocidins via regioselective and diastereoselective phosphine-catalyzed [3 + 2]-cycloadditions to 5-methylenehydantoins

The phosphine-catalyzed [3 + 2]-cycloaddition of 5-methylenehydantoins 4 with the ylides 5, derived from addition of tributylphosphine to the 2-butynoic acid derivatives, 6a-d, gives spiro-heterocyclic products. The camphor sultam derivative 6b gives optically active products. Noteable was that the ylides derived from ethyl 2-butynoate and the 3-(2-butynoyl)-1,3-oxazolidin-2-one derivatives 6c and 6d gave spiro-heterocyclic products with reverse regioselectivities. The N,N-dibenzylprotected cycloadduct has been converted to carbocyclic hydantocidin and 6,7-diepi-carbocyclic hydantocidin.