673470-48-9

Basic information

• Product Name: Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[(trifluoroacetyl)amino]-, phenylmethyl ester, (3S)-
• CAS NO: 673470-48-9
• Molecular Formula: C17H15F3N2O7
• Molecular Weight: 416.311
• Mol File: 673470-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[(trifluoroacetyl)amino]-, phenylmethyl ester, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[(trifluoroacetyl)amino]-, phenylmethyl ester, (3S)-(673470-48-9)
• EPA Substance Registry System: Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[(trifluoroacetyl)amino]-, phenylmethyl ester, (3S)-(673470-48-9)

Safety Data

• Hazardous Substances Data: 673470-48-9(Hazardous Substances Data)

Upstream product

• 2177-63-1 (S)-2-amino-4-(benzyloxy)-4-oxobutanoic acid 

Downstream Products

• 673470-45-6 4-iodo-3S-(2,2,2-trifluoroacetylamino)butanoic acid benzyl ester 
• 673470-50-3 4-hydroxy-3S-(2,2,2-trifluoroacetylamino)butanoic acid benzyl ester 

Relevant articles and documents

Direct synthesis of unprotected phenols using palladium-catalysed cross coupling reactions of functionalised organozinc reagents

Palladium-catalysed reaction of unprotected 2-, 3-, and 4-iodophenols with a range of amino acid derived organozinc reagents (not used in excess) gives the expected products in good to excellent yield, demonstrating that carbon-zinc bonds are not protonated by acidic phenols under the conditions of palladium-catalysed coupling reactions.