6736-68-1 Usage
Description
(2'-METHOXYCARBONYL) PHENYL-2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE, also known as Maclipain-2, is a chemical compound that belongs to the class of glycosides. It is a derivative of the sugar molecule 2-deoxyglucose and is commonly used in biochemical and pharmacological research.
Used in Pharmaceutical Industry:
(2'-METHOXYCARBONYL) PHENYL-2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE is used as a potential antiviral agent for its inhibitory activity against HIV protease.
Used in Biochemical Research:
(2'-METHOXYCARBONYL) PHENYL-2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE is used as a substrate for studying enzyme specificity and as a tool for understanding enzymatic reactions.
Used in Development of Glycosidase Inhibitors:
(2'-METHOXYCARBONYL) PHENYL-2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE is used in the development of new glycosidase inhibitors, which could have implications for the treatment of metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 6736-68-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,3 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6736-68:
(6*6)+(5*7)+(4*3)+(3*6)+(2*6)+(1*8)=121
121 % 10 = 1
So 6736-68-1 is a valid CAS Registry Number.
6736-68-1Relevant articles and documents
Neighbouring acetamido-group participation in reactions of derivatives of 2-acetamido-2-deoxy-D-glucose.
Ballardie,Capon,Dearie,Foster
, p. 79 - 92,88,90 (2007/10/04)
Kinetic measurements suggest that neighbouring acetamido-group participation occurs in the spontaneous hydrolysis and methanolysis of o-carboxyphenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside and in the spontaneous hydrolysis of 2,4-dinitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside and 2-acetamido-2-deoxy-beta-D-glycopyranosyl fluoride. The methanolyses of these compounds proceed with predominant retention of configuration which is also consistent with neighbouring acetamido-group participation. The oxazoline intermediate which would arise from such a process was detected during methanolysis of 2-acetamido-2-deoxy-beta-D-glucopyranosyl fluoride in the presence of bases by n.m.r., i.r., and u.v. spectroscopy. Attempts to isolate the oxazoline were unsuccessful.
