67370-87-0

Basic information

• Product Name: 5-Methyl-1,5-diazacyploheptadecan-6-one
• Synonyms: 5-Methyl-1,5-diazacyploheptadecan-6-one
• CAS NO: 67370-87-0
• Molecular Formula: C16H32N2O
• Molecular Weight: 268.44
• Mol File: 67370-87-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 160-180 °C(Press: 0.001 Torr)
• Appearance: /
• Density: 0.879±0.06 g/cm3(Predicted)
• PKA: 10.82±0.20(Predicted)
• CAS DataBase Reference: 5-Methyl-1,5-diazacyploheptadecan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-1,5-diazacyploheptadecan-6-one(67370-87-0)
• EPA Substance Registry System: 5-Methyl-1,5-diazacyploheptadecan-6-one(67370-87-0)

Safety Data

• Hazardous Substances Data: 67370-87-0(Hazardous Substances Data)

Upstream product

• 67171-82-8 7-(2-oxo-azacyclotridec-1-yl)-4-azaheptanenitrile 

Relevant articles and documents

Transamidation Reactions. Part 11) N-Substituted 3-Aminopropanenitriles and 2-Aminoacetonitriles as Schiff-Base Equivalents

In presence of a strong base, the 13-membered cyclic compound 3 yielded, by loss of acetonitrile or its equivalent, the bicyclic product 5 instead of the 17-membered compound 4 as expected (Scheme 2).Investigation of model compounds (Scheme 4) and of model reactions (Schemes 5 and 6) led to the conclusion that the reaction proceeds via an intermediate formaldehyde imine; a Schiff base, e. g. 3b (Scheme 5), which reacts intra- and intermolecularly with a nucleophile to form a Mannich-type product.It seems to be a general principle that N-substituted 3-aminopropanenitrile and 2-aminoacetonitrile derivatives behave in the presence of a strong base as Schiff-base equivalents (Scheme 5 and 6).