67392-08-9Relevant academic research and scientific papers
Synthesis (in ent-form) of a Novel Jalcaguaianolide from Ferula arrigonii Bocchieri
Delair, Philippe,Kann, Nina,Greene, Andrew E.
, p. 1651 - 1652 (1994)
A recently isolated isodehydrocostus lactone from the genus Ferula (Umbelliferae) has been stereoselectively prepared from ent-form from α-santonin by a photochemical transformation to O-acetylisophotosantonic lactone followed by functional group manipulations that conclude with a one-step γ-butyrolactone -> Δα,β-butenolide conversion; the synthesis corroborates both the structure and the relative and absolute stereochemistry that have been proposed for the natural product.
Isolation and Crystal Structure of Grilactone, a New Guaianolide from Ferula oopoda
Malone, John F.,Parves, Masood,Karim, Amna,McKervey, M. Anthony,Ahmad, Iftikhar,Bhatty, Mahammad K.
, p. 1683 - 1685 (2007/10/02)
The chief constituent of the essential oils from the roots of the plant Ferula oopoda is the sesquiterpene guaianolide, grilactone, whose structure has been determined by an X-ray diffraction study.Crystals are orthorhombic, space group P212121 with four molecules in a cell of dimensions a=9.90 (2), b=14.98 (2), c=8.74 (2) Angstroem.The structure was refined by least squares to R 0.079.Grilactone has a cis-anti-cis-configuration at the ring junctions.
