674-53-3

Usage

Uses

Used in Chemical Synthesis Industry:
4,4,4-TRIFLUOROBUT-2-EN-1-OL is used as a chemical intermediate for the production of other chemicals. Its high reactivity makes it a valuable component in the synthesis of various compounds, contributing to the development of new materials and substances with specific applications in different fields.
Given the provided materials, there are no specific applications listed for 4,4,4-TRIFLUOROBUT-2-EN-1-OL other than its use as an intermediate in chemical production. However, due to its reactivity and toxicity, it is crucial to handle 4,4,4-TRIFLUOROBUT-2-EN-1-OL with extreme care to prevent any adverse effects on health or the environment. Further research and development may reveal additional uses for 4,4,4-TRIFLUOROBUT-2-EN-1-OL in specialized applications.

InChI:InChI=1/C4H5F3O/c5-4(6,7)2-1-3-8/h1-2,8H,3H2/b2-1+

Upstream product

• 728040-39-9 4,4,4-trifluorobutenol acetate 
• 2314-97-8 iodotrifluoromethane 
• 107-19-7 propargyl alcohol 
• 75-63-8 Bromotrifluoromethane 
• 25597-16-4 ethyl 4,4,4-trifluorobut-2-enoate 
• 674-35-1 4,4,4-Trifluor-2-iod-buten-(2)-ol-(1) 

Downstream Products

• 1536-55-6 γ-Trifluormethylallyl-p-brombenzolsulfonat 
• 286836-16-6 1-(1-trifluoromethylprop-1-en-3-yloxy)-2-bromo-4-fluorobenzene 
• 871917-92-9 4,4,4-trifluoro-2-butenyl p-toluenesulfonate 
• 406-88-2 4,4,4-trifluorocrotonaldehyde 

Relevant academic research and scientific papers

Practical synthesis of 4,4,4-trifluorocrotonaldehyde: A versatile precursor for the enantioselective formation of trifluoromethylated stereogenic centers via organocatalytic 1,4-additions

The practical synthesis of 4,4,4-trifluorocrotonaldehyde (1) and its application to enantioselective 1,4-additions are described. The organocatalytic 1,4-addition of 1 with several nucleophiles such as heteroaromatics, alkylthiols and aldoximes afforded t

PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES BY INTRAMOLECULAR ALLYLATION

The present invention relates to a new process for preparing 2-oxo-1-pyrrolidine derivatives of general formula (I), comprising the cyclisation of an intermediate of general formula (II) wherein the substituents are as defined in the specification.

Ultrasound-Promoted Selective Perfluoroalkylation on the Desired Position of Organic Molecules

Perfluoroalkylzinc iodides or bromides wich were prepared from perfluoroalkyl iodides or bromides and zinc powder in N,N-dimethylformamide or tetrahydrofuran with ultrasonic irradiation were found to behave as potential perfluoroalkylating reagents for the preparation of a wide variety of perfluoroalkylated compounds.Especially, the ultrasound-promoted asymmetric induction with perfluoroalkyl group on the asymmetrical carbon was achieved by the reaction of perfluoroalkyl halides with optically active enamines in the presence of zinc powder and a catalytic amount of dichlorobis(?-cyclopentadienyl)titanium.

PREPARATION OF TRIFLUOROMETHYLATED ALLYLIC ALCOHOLS FROM TRIFLUOROACETALDEHYDE AND ORGANOMETALLIC COMPOUNDS

A number of allylic alcohols bearing a trifluoromethyl group at the α- or γ-position, and α-trifluoromethylated γ-enols and -ynols were prepared by the reaction of trifluoroacetaldehyde with a variety of organometallic compounds.Most of the Reformatsky- or Grignard-type reactions required promotion by ultrasonic irradiation.

ULTRASOUND-PROMOTED HYDRPERFLUOROALKYLATION OF ALKYNES WITH PERFLUOROALKYLZINC IODIDE AND COPPER(I) IODIDE

The reaction of perfluoroalkyl iodides with terminal alkynes and ultrasonically dispersed zinc in the presence of copper(I) iodide proceeded smoothly to give the corresponding vinyl perfluoroalkylides in good yields.