674-70-4Relevant academic research and scientific papers
Rapid and Efficient Synthesis of ω-Alkylenediphosphoric Acids from Phosphorus Oxychloride
Meziane, Dalila,Elias, Abdelhamid,Guénin, Erwann
, (2016)
The aim of this investigation was to develop an efficient, rapid, and selective method for the synthesis of ω-alkylenediphosphoric acids (HO)2(O)P-O-(CH2)n-O-P(O)(OH)2 from reaction of several diols with phosphorus oxychloride. The reaction was investigated using three methodologies: (i) presence of a base, (ii) classical heating, and (iii) use of microwave irradiation. Influence of reaction temperature and molar ratio of reagents, as well as the nature of the solvent, was studied using these three different methods.
Synthesis and antibacterial activity of novel enolphosphate derivatives
Grison, Claude,Barthes, Nicolas,Finance, Chantal,Duval, Raphael E.
experimental part, p. 218 - 223 (2010/09/08)
A new class of enolphosphates derivatives, the 1-alkenyldiphosphates, was designed and a rapid and efficient synthesis for these compounds was developed. These new molecules showed interesting in vitro antibacterial activities (MIC) against Gram-positive bacteria (Staphylococcus aureus) and Gram-negative pathogens including Pseudomonas aeruginosa and Escherichia coli.
