67422-75-7

Upstream product

• 116705-32-9 6-((E)-2-Dimethylamino-vinyl)-1-methyl-5-nitro-3-(4-nitro-phenyl)-1H-pyrimidine-2,4-dione 
• 104396-49-8 1,6-dimethyl-5-nitro-3-(4-nitro-phenyl)-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Ring Transformation of Pyrimidines. Synthesis of 4-Alkylaminopyridin-2-ones by Alkaline Hydrolysis of 6-(2-Dimethylaminovinyl)uracils

Alkaline hydrolysis of 1,3-disubstituted 6-(2-dimethylaminovinyl)uracils 2 induced a novel ring transformation giving 4-alkylaminopyridin-2-ones 3 via ring-opening and ring-closure processes.The 4-methylamino-3-nitropyridin-2-one (3a) thus obtained was employed for the synthesis of 3-deazahypoxanthine derivative 8. 4-Alkylamino-3-cyanopyridin-2-ones 11, ricinine analogs, were also prepared by the reaction of 4-chloro-3-cyano-1-methylpyridin-2-one (10) with amines.