674287-63-9 Usage
General Description
5-Bromo-1H-1,2,4-triazole-3-carboxylic acid is a chemical compound with the molecular formula C4H2BrN3O2. It falls under the category of triazoles, which are a class of nitrogen-containing heterocycles that have widespread application in the pharmaceutical, chemical, and agricultural industries. The halogen atom (bromine) present in its structure can make it a highly reactive molecule capable of participating in various types of chemical reactions. 5-BROMO-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID may be used as a starting material or intermediate in the synthesis of more complex organic compounds. Its hazardous properties and safety data are generally provided by the Material Safety Data Sheet (MSDS).
Check Digit Verification of cas no
The CAS Registry Mumber 674287-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,4,2,8 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 674287-63:
(8*6)+(7*7)+(6*4)+(5*2)+(4*8)+(3*7)+(2*6)+(1*3)=199
199 % 10 = 9
So 674287-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H2BrN3O2/c4-3-5-1(2(8)9)6-7-3/h(H,8,9)(H,5,6,7)
674287-63-9Relevant articles and documents
Chemoenzymatic method of 1,2,4-triazole nucleoside synthesis: Possibilities and limitations
Konstantinova,Chudinov,Fateev,Matveev,Zhurilo,Shvets,Miroshnikov
, p. 53 - 71 (2013/04/10)
Possibilities and limitations of chemoenzymatic synthesis of novel structural analogues of an antiviral preparation of Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were established. A synthesis of various amides of 1H-1,2,4-triazole-3-carboxylic acid and its 5-substituted analogues - potential substrates of purine nucleoside phosphorylase - has been described. Comparative efficiency of preparation methods of these amides, as well as the methods of introduction of functional groups to the C5 position of heterocyclic system, were investigated. Novel analogues of Ribavirin containing various substitutes in the carboxamide group were synthesized. A biotechnological method was developed for the preparation of 1-β-D-ribofuranozyl-1,2,4-triazole-3-carbonitryl, an intermediate in the synthesis of Viramidine, the modern analogue of Ribavirin.
