67431-17-8Relevant academic research and scientific papers
Synthesis of methoxyfumimycin with 1,2-addition to ketimines
Gross, Patrick J.,Hartmann, Caroline E.,Nieger, Martin,Braese, Stefan
supporting information; experimental part, p. 229 - 232 (2010/04/24)
(Chemical Equation Presented) The synthesis of (±)-methoxyfumimycin, a potential new bacterial peptide deformylase (PDF) inhibitor, is reported. To generate the stereogenic fully substituted carbon, the key step is a 1,2-addition of amethylGrignard reagent to a ketimine. The overall synthetic strategy involves a Dakin oxidation of a vanillin derivative, Friedel-Crafts acylation, Claisen rearrangement, lactonization, and rhodium-catalyzed olefin isomerization.
Synthesis of (±)-likonide B (smenochromene D) using a regioselective Claisen rearrangement, separation of the enantiomers and stereochemical assignment
Bruder, Marjorie,Smith, Stephen J.,Blake, Alexander J.,Moody, Christopher J.
experimental part, p. 2127 - 2134 (2009/09/04)
A synthesis of the unusual ansa-bridged farnesyl hydroquinone derivative likonide B in racemic form is described. The natural product, also known as smenochromene D, was obtained from geranylacetone by a route in which the key steps are a regioselective m
Baeyer-Villiger oxidation of β-aryl substituted unsaturated carbonyl compounds with hydrogen peroxide and catalytic selenium dioxide
Guzman,Mendoza,Garcia,Garibay,Oliveras,Maldonado
, p. 2121 - 2133 (2007/10/02)
A simple and cheap oxidative procedure using 30% H2O2 and catalytic SeO2 allows to transform 2-aralkylidenecycloalkanones and hydroxy- or alkoxybenzaldehydes to give, in high yields, enollactones and arylformates, respectively.
IMPROVED OXIDATION PROCEDURE WITH AROMATIC PEROXYACIDS
Camps, F.,Coll, J.,Messeguer, A.,Pericas, M.A.
, p. 3895 - 3896 (2007/10/02)
The application of the m-Chloroperbenzoic acid-potassium fluoride system in the Baeyer-Villinger oxidation of aromatic aldehydes and in the epoxidation of olefins has been studied.
