674335-93-4

Upstream product

• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 674336-06-2 2-[(2S,4R,6S)-4-Benzyloxy-6-((S)-2-hydroxy-pent-4-enyl)-tetrahydro-pyran-2-ylmethyl]-6-hydroxy-benzoic acid 
• 674336-01-7 2-(tert-Butyl-diphenyl-silanyloxy)-6-((2S,4S,6R)-4-hydroxy-6-methoxymethyl-tetrahydro-pyran-2-ylmethyl)-benzoic acid methyl ester 
• 674336-20-0 2-((2S,4R,6R)-4-Benzyloxy-6-formyl-tetrahydro-pyran-2-ylmethyl)-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-17-5 2-(tert-Butyl-diphenyl-silanyloxy)-6-[(2S,4R,6R)-4-(2-chloro-acetoxy)-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl]-benzoic acid methyl ester 
• 674336-02-8 2-(tert-Butyl-diphenyl-silanyloxy)-6-[(2S,4R,6R)-4-(2-chloro-acetoxy)-6-methoxymethyl-tetrahydro-pyran-2-ylmethyl]-benzoic acid methyl ester 
• 674335-94-5 2-[(2S,4R,6R)-4-Benzyloxy-6-(2-oxo-ethyl)-tetrahydro-pyran-2-ylmethyl]-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-04-0 2-((2S,4R,6R)-4-Benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl)-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-03-9 2-[6-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-pyran-2-ylmethyl]-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-05-1 2-[(2S,4R,6S)-4-Benzyloxy-6-((S)-2-hydroxy-pent-4-enyl)-tetrahydro-pyran-2-ylmethyl]-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-18-6 2-[(2S,4R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-chloro-acetoxy)-tetrahydro-pyran-2-ylmethyl]-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 674336-19-7 2-[4-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-ylmethyl]-6-(tert-butyl-diphenyl-silanyloxy)-benzoic acid methyl ester 
• 107-30-2 chloromethyl methyl ether 
• 674336-21-1 2-[(2S,4R,6S)-4-Benzyloxy-6-((S)-2-hydroxy-pent-4-enyl)-tetrahydro-pyran-2-ylmethyl]-6-hydroxy-benzoic acid cyanomethyl ester 

Downstream Products

• 674336-07-3 (1S,11S,13R,15R)-11-Allyl-15-benzyloxy-7-methoxymethoxy-10,17-dioxa-tricyclo[11.3.1.0^3,8]heptadeca-3⁽⁸⁾,4,6-trien-9-one 
• 674336-08-4 ((1S,11R,13R,15R)-15-Benzyloxy-7-methoxymethoxy-9-oxo-10,17-dioxa-tricyclo[11.3.1.0^3,8]heptadeca-3⁽⁸⁾,4,6-trien-11-yl)-acetaldehyde 

Relevant academic research and scientific papers

Total Synthesis of (-)-Apicularen A

Complete details of an asymmetric synthesis of apicularen (1) are described. The synthesis has been accomplished using a highly diastereo- and enantioselective [4 + 2] annulation for the assembly of the functionalized pyran core. An underdeveloped lactoni