674359-50-3Relevant academic research and scientific papers
Terpenoid and phenolic constituents from the roots of Ilex pubescens
Zhou, Xu-Dong,Xu, Xiang-Wei,Xi, Yi-Yuan,Zhou, Yuan
, (2019/08/20)
Five new metabolites, including two monoterpene glycosides Pubescenosides L–M (1–2) and three phenolic glycosides, Pubescenosides N-P (3–5), along with nineteen known ones, including liganoids, hemiterpenoids and caffeoylquinic acid derivates, were isolated from the roots of Ilex pubescens. Their structures were elucidated from extensive spectroscopic analysis, including 1D and 2D NMR experiments. This study is the first to report monoterpene glycosides with β-pinene aglycone in Aquifoliaceae. Nine of these compounds were evaluated in vitro for their anti-platelet aggregation activities. Among them, compounds 3 and 4 showed moderate inhibitory activities on ADP-induced blood platelet aggregation [inhibition (%): 32.3 and 33.6, respectively] as compared to aspirin.
Glycosides from the root of Iodes cirrhosa
Gan, Maoluo,Zhang, Yanling,Lin, Sheng,Liu, Mingtao,Song, Weixia,Zi, Jiachen,Yang, Yongchun,Fan, Xiaona,Shi, Jiangong,Hu, Jinfeng,Sun, Jiandong,Chen, Naihong
experimental part, p. 647 - 654 (2009/04/04)
Seven new neolignan glycosides (1-7), two arylglycerol glycosides (8, 9), and 18 known glycosides have been isolated from an ethanolic extract of the root of Iodes cirrhosa. Their structures including absolute configurations were determined by spectroscop
Isolation of α-glusosidase inhibitors from hyssop (Hyssopus officinalis)
Matsuura, Hideyuki,Miyazaki, Hiroyuki,Asakawa, Chikako,Amano, Midori,Yoshihara, Teruhiko,Mizutani, Junya
, p. 91 - 97 (2007/10/03)
α-Glucosidase inhibitory activity was found in aqueous methanol extracts of dried hyssop (Hyssopus officinalis) leaves. Active principles against α-glucosidase, prepared from rat small intestine acetone powders, were isolated and characterized. The structures of these isolated compounds were determined to be (7S, 8S)-syringoylglycerol-9-O-(6′-O-cinnamoyl)- β-D-glucopyranoside and (7S, 8S)-syringoylglycerol 9-O-β-D- glucopyranoside by analysis of physical and spectroscopic data (FDMS, 1H NMR, 13C NMR, HMQC, and HMBC experiments) together with chemical syntheses.
