67451-16-5

Usage

Uses

Used in Pharmaceutical Industry:
4-ACETOXYPHENYL METHYL SULFONE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new therapeutic agents. Its chemical structure allows for the creation of various organic compounds that can be further utilized in medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, 4-ACETOXYPHENYL METHYL SULFONE is employed as a key building block for the production of complex organic molecules. Its unique structure facilitates the formation of diverse chemical entities that can be tailored for specific applications.
Used in Anti-inflammatory Applications:
4-ACETOXYPHENYL METHYL SULFONE is used as an anti-inflammatory agent due to its potential to inhibit the production of proinflammatory mediators. This property makes it a promising candidate for the treatment of conditions characterized by inflammation.
Used in Antioxidant Applications:
As an antioxidant, 4-ACETOXYPHENYL METHYL SULFONE is utilized to protect cells from oxidative stress and damage. Its ability to neutralize reactive oxygen species contributes to its potential use in preventing and treating diseases associated with oxidative stress.

Upstream product

• 50910-13-9 4-methylsulfanyl(methylcarbonyloxy)benzene 
• 14763-60-1 4-methanesulfonyl-phenol 
• 108-24-7 acetic anhydride 
• 1073-72-9 4-hydroxythioanisole 

Downstream Products

• 20951-24-0 2-acetyl-4-(methylsulfonyl)phenol 
• 14763-60-1 4-methanesulfonyl-phenol 
• 20951-25-1 1-(3-Bromo-2-hydroxy-5-methanesulfonyl-phenyl)-ethanone 
• 84942-32-5 2-Amino-6-ethyl-4-methanesulfonyl-phenol; hydrochloride 
• 70978-46-0 2-Hydroxy-5-methylsulfonyl-3-nitroacetophenon 

Relevant academic research and scientific papers

An environmentally benign and selective electrochemical oxidation of sulfides and thiols in a continuous-flow microreactor

A practical and environmentally benign electrochemical oxidation of thioethers and thiols in a commercially-available continuous-flow microreactor is presented. Water is used as the source of oxygen to enable the oxidation process. The oxidation reaction utilizes the same reagents in all scenarios and the selectivity is solely governed by the applied potential. The procedure exhibits a broad scope and good functional group compatibility providing access to various sulfoxides (15 examples), sulfones (15 examples) and disulfides (6 examples). The use of continuous flow allows the optimal reaction parameters (e.g. residence time, applied voltage) to be rapidly assessed, to avoid mass- and heat-transfer limitations and to scale the electrochemistry.

Rhodium-catalyzed direct ortho-alkenylation of phenyl sulfones with alkynes utilizing sulfonyl function as modifiable directing group

Abstract The ortho-selective alkenylation of phenyl sulfones with alkynes proceeds effectively in the presence of a cationic Cp?-rhodium(III) catalyst together with an appropriate carboxylic acid involving regioselective C-H bond cleavage directed by the sulfonyl function. An (ortho-alkenylated phenyl) methyl sulfone prepared by this hydroarylation method undergoes palladium-catalyzed α-arylation and subsequent diastereoselective cyclization to directly produce the corresponding thiochromane 1,1-dioxide derivatives.

Selected sulfonyl compounds as anticancer/antimalarial agents

The synthesis and biological testing of a series of sulfonyl phenols and sulfonyl aryl methyl ethers has revealed that p-methoxyphenyl p-toluenesulfonate is a very selective and effective antimalarial agent which shows pronounced activity against human skin cancer cells. Application of a counter-attack strategy permits the direct preparation of the requisite tosylate ether from the bis(tosylate) of dihydroquinone.