67451-16-5

Basic information

• Product Name: 4-ACETOXYPHENYL METHYL SULFONE
• Synonyms: 4-ACETOXYPHENYL METHYL SULFONE
• CAS NO: 67451-16-5
• Molecular Formula: C₉H₁₀O₄S
• Molecular Weight: 214.24
• Mol File: 67451-16-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 372.3±34.0 °C at 760 mmHg
• Flash Point: 178.9±25.7 °C
• Appearance: /
• Density: 1.3±0.1 g/cm³
• CAS DataBase Reference: 4-ACETOXYPHENYL METHYL SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETOXYPHENYL METHYL SULFONE(67451-16-5)
• EPA Substance Registry System: 4-ACETOXYPHENYL METHYL SULFONE(67451-16-5)

Safety Data

• Hazardous Substances Data: 67451-16-5(Hazardous Substances Data)

Usage

General Description

4-ACETOXYPHENYL METHYL SULFONE is a chemical compound with the molecular formula C9H10O4S. It is a sulfone derivative with a phenyl methyl group and an acetoxy group attached to the phenyl ring. 4-ACETOXYPHENYL METHYL SULFONE is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has also been investigated for its potential anti-inflammatory and antioxidant properties. Additionally, 4-ACETOXYPHENYL METHYL SULFONE is known for its ability to inhibit the production of proinflammatory mediators, making it a potential candidate for the development of new therapeutic agents.

Upstream product

• 1073-72-9 4-hydroxythioanisole 
• 14763-60-1 4-methanesulfonyl-phenol 
• 108-24-7 acetic anhydride 
• 50910-13-9 4-methylsulfanyl(methylcarbonyloxy)benzene 

Downstream Products

• 20951-25-1 1-(3-Bromo-2-hydroxy-5-methanesulfonyl-phenyl)-ethanone 
• 84942-32-5 2-Amino-6-ethyl-4-methanesulfonyl-phenol; hydrochloride 
• 70978-46-0 2-Hydroxy-5-methylsulfonyl-3-nitroacetophenon 
• 14763-60-1 4-methanesulfonyl-phenol 
• 20951-24-0 2-acetyl-4-(methylsulfonyl)phenol 

Relevant articles and documents

An environmentally benign and selective electrochemical oxidation of sulfides and thiols in a continuous-flow microreactor

A practical and environmentally benign electrochemical oxidation of thioethers and thiols in a commercially-available continuous-flow microreactor is presented. Water is used as the source of oxygen to enable the oxidation process. The oxidation reaction utilizes the same reagents in all scenarios and the selectivity is solely governed by the applied potential. The procedure exhibits a broad scope and good functional group compatibility providing access to various sulfoxides (15 examples), sulfones (15 examples) and disulfides (6 examples). The use of continuous flow allows the optimal reaction parameters (e.g. residence time, applied voltage) to be rapidly assessed, to avoid mass- and heat-transfer limitations and to scale the electrochemistry.

Selected sulfonyl compounds as anticancer/antimalarial agents

The synthesis and biological testing of a series of sulfonyl phenols and sulfonyl aryl methyl ethers has revealed that p-methoxyphenyl p-toluenesulfonate is a very selective and effective antimalarial agent which shows pronounced activity against human skin cancer cells. Application of a counter-attack strategy permits the direct preparation of the requisite tosylate ether from the bis(tosylate) of dihydroquinone.