67452-85-1 Usage
Uses
1-Benzoyl-3-piperidinone is synthesized from 3-Hydroxypiperidine (H952190). 3-Hydroxypiperidine is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. 3-Hydroxypiperidine is also a metabolite of Piperidine (P479985), Piperidine is an organic heterocyclic amine widely used as building block and reagent in the synthesis of organic compounds including pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 67452-85-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,4,5 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 67452-85:
(7*6)+(6*7)+(5*4)+(4*5)+(3*2)+(2*8)+(1*5)=151
151 % 10 = 1
So 67452-85-1 is a valid CAS Registry Number.
67452-85-1Relevant articles and documents
Preparation method N-substituted piperidine -3- ketone (by machine translation)
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Paragraph 0094-0097, (2020/03/25)
The invention provides N -substituted piperi- 3 3-ketone preparation method, which uses acrylonitrile (II) and nitromethane as raw materials to obtain 4 -substituted-N-alkoxycarbonylmethyl- 4 4-aminobutyronitrile (III), to obtain 4 - substituent - N N-alkoxycarbonylmethyl( (IV),substituted-piperi- 3 3-one N - by addition reaction and decarboxylation to yield (V),substituted-piperidin-3-one according. to the present invention by two-time substituent reaction, reaction, and decarboxylation to obtain, a compound obtained from, N -substituted-piperidin-3-one of, the invention. (I). The method is simple, process and, times of reaction and decarboxylation. (by machine translation)