67453-80-9

Basic information

• Product Name: N-(4-METHOXY-PHENYL)-GUANIDINE
• Synonyms: N-(4-METHOXY-PHENYL)-GUANIDINE;1-(4-Methoxyphenyl)guanidine
• CAS NO: 67453-80-9
• Molecular Formula: C₈H₁₁N₃O
• Molecular Weight: 165.19
• Mol File: 67453-80-9.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(4-METHOXY-PHENYL)-GUANIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-METHOXY-PHENYL)-GUANIDINE(67453-80-9)
• EPA Substance Registry System: N-(4-METHOXY-PHENYL)-GUANIDINE(67453-80-9)

Safety Data

• Hazardous Substances Data: 67453-80-9(Hazardous Substances Data)

Usage

General Description

N-(4-METHOXY-PHENYL)-GUANIDINE, also known as 36635-61-7 (CAS Number), is a synthetic, organic compound which falls into the category of guanidines. Guanidines are strong alkali compounds with the formula (NH2)2C=NH that exist in a variety of forms ranging from solids to colorless gaseous compounds. N-(4-METHOXY-PHENYL)-GUANIDINE is specific in its structure, containing a 4-methoxy-phenyl group (a phenyl ring with a methoxy group located on the 4th carbon). N-(4-METHOXY-PHENYL)-GUANIDINE is generally used in various forms of scientific research, often linked to chemical reactions. Its exact properties such as its density, melting point or boiling point may vary, depending on its state and environmental conditions.

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 60-29-7 diethyl ether 
• 41988-52-7 N-cyano-N'-(4-methoxyphenyl)guanidine 
• 14527-26-5 2-methylisothiourea sulphate 
• 104-94-9 4-methoxy-aniline 
• 100-17-4 para-methoxynitrobenzene 
• 112677-02-8 (4-methoxyphenyl)guanidine carbonate 
• 420-04-2 CYANAMID 
• 1026100-78-6 C₂₃H₂₀N₂O₃S 
• 158478-72-9 N,N′-bis(tert-butoxycarbonyl)-N′′-(4-methoxyphenyl)guanidine 
• 20265-97-8 p-anisidine hydrochloride 

Downstream Products

• 66491-63-2 1-(4-methoxy-phenyl)-5-phenyl-biguanide 
• 93002-44-9 1-isopropyl-5-(4-methoxy-phenyl)-biguanide 
• 23951-85-1 N-(4-methoxylphenyl)-4,6-dimethyl-2-pyrimidinamine 
• 1203795-19-0 N-(4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)pyrimidin-2-amine 
• 1550369-51-1 2-amino-1-(4-methoxyphenyl)-1H-benzo[d]imidazol-6-ol 
• 1403963-23-4 (E)-ethyl 3-(2-guanidino-5-methoxyphenyl)acrylate hydrochloride 
• 92910-71-9 1,4-dihydro-N²-(4-methoxyphenyl)-6-methyl-4-phenyl-2-pyrimidinamine 
• 14294-05-4 N-<(4-Methoxy-phenyl)-carbamimidoyl>-N'-(tert.-butyl)-thioharnstoff 
• 51594-51-5 1-(4-methoxyphenyl)-3-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)guanidine 

Relevant articles and documents

Discovery of CDK5 Inhibitors through Structure-Guided Approach

Specific abrogation of cyclin-dependent kinase 5 (CDK5) activity has been validated as a viable approach for the development of anticancer agents. However, no selective CDK5 inhibitor has been reported to date. Herein, a structure-based in silico screenin

IMIDAZOPYRIDINE AMINE COMPOUND, METHOD FOR PRODUCING THE SAME AND USE OF THE SAME

PROBLEM TO BE SOLVED: To provide: an unprecedented imidazopyridine amine compound having excellent neurocyte differentiation promoting activity and high safety; a pharmaceutically acceptable salt or a solvate thereof; an application thereof; and a production method therefor. SOLUTION: There are provided: an imidazopyridine amine compound represented by the formula 1; a pharmaceutical composition comprising a pharmaceutically acceptable salt or a solvate thereof; and a neurocyte differentiation promotor. [R1 to R3 each independently represent H, halogen or the like; R1 and R2 or R1 and R3 may form an unsubstituted/substituted 5- to 8-membered heterocyclic ring together with an N atom; m represents an integer of 0 to 2; and A ring represents a substituted/unsubstituted carbon ring or a hetero ring.] SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

Direct guanylation of amino groups by cyanamide in water: Catalytic generation and activation of unsubstituted carbodiimide by scandium(iii) triflate

Guanylation proceeded efficiently upon treatment of the various amines with cyanamide in the presence of catalytic amounts of scandium(III) triflate under mild conditions. The method did not require the guanylation reagents to be preactivated, and the reaction proceeded efficiently in water. The method, therefore, has practical utility for substrates that dissolve only in aqueous solutions, for example, peptides or pharmacologically important compounds. Georg Thieme Verlag Stuttgart New York.