67467-83-8 Usage
Uses
Different sources of media describe the Uses of 67467-83-8 differently. You can refer to the following data:
1. Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the USA for such indications. The major advantage of this new antimycotic drug presumably lies in its potential for use as 5% nail lacquer in the treatment of onychomycosis caused by dermatophytes and Candida spp.
2. Antimycotic.
3. Amorolfine is a novel antifungal agent used in the treatment of cutaneous fungal disease.
Side effects
Topical application of amorolfine (5% nail lacquer and 0.25% cream) is generally well tolerated, with up to 5% of patients reporting minor symptoms. In patients using the nail lacquer, these events included burning, itching, redness, and local pain, which were toleratable and confined to the application site. Adverse effects of scaling, weeping, blistering, and edema have also been described for the cream formulation.
Brand name
Loceryl (Hoffmann-LaRoche).
Check Digit Verification of cas no
The CAS Registry Mumber 67467-83-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,4,6 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67467-83:
(7*6)+(6*7)+(5*4)+(4*6)+(3*7)+(2*8)+(1*3)=168
168 % 10 = 8
So 67467-83-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H35NO/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22/h8-11,16-18H,7,12-15H2,1-6H3/t16?,17-,18+