674769-41-6

Basic information

• Product Name: 1,12-Tridecadien-4-one, 11-(benzoyloxy)-8-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,10-dimethoxy- 2,3,3-trimethyl-5-(phenylmethoxy)-, (5R,6R,8S,10R,11R)-
• CAS NO: 674769-41-6
• Molecular Formula: C38H56O7Si
• Molecular Weight: 652.944
• Mol File: 674769-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,12-Tridecadien-4-one, 11-(benzoyloxy)-8-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,10-dimethoxy- 2,3,3-trimethyl-5-(phenylmethoxy)-, (5R,6R,8S,10R,11R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,12-Tridecadien-4-one, 11-(benzoyloxy)-8-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,10-dimethoxy- 2,3,3-trimethyl-5-(phenylmethoxy)-, (5R,6R,8S,10R,11R)-(674769-41-6)
• EPA Substance Registry System: 1,12-Tridecadien-4-one, 11-(benzoyloxy)-8-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,10-dimethoxy- 2,3,3-trimethyl-5-(phenylmethoxy)-, (5R,6R,8S,10R,11R)-(674769-41-6)

Safety Data

• Hazardous Substances Data: 674769-41-6(Hazardous Substances Data)

Upstream product

• 674769-34-7 1-benzyloxy-3,3,4-trimethyl-pent-4-en-2-one 
• 674769-36-9 Benzoic acid (2S,3S,4R,6R)-6-((2R,3R)-3-benzyloxy-2-hydroxy-5,5,6-trimethyl-4-oxo-hept-6-enyl)-2-bromomethyl-4-methoxy-tetrahydro-pyran-3-yl ester 
• 674769-43-8 Benzoic acid (2S,3S,4R,6S)-6-((2R,3R)-3-benzyloxy-2-methoxy-5,5,6-trimethyl-4-oxo-hept-6-enyl)-2-bromomethyl-4-methoxy-tetrahydro-pyran-3-yl ester 
• 674769-32-5 Benzoic acid (2S,3S,4R,6R)-6-allyl-2-bromomethyl-4-methoxy-tetrahydro-pyran-3-yl ester 
• 674769-33-6 Benzoic acid (2S,3S,4R,6S)-2-bromomethyl-4-methoxy-6-(2-oxo-ethyl)-tetrahydro-pyran-3-yl ester 
• 674769-29-0 (2S,4aR,8R,8aS)-6,8-Dimethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 674769-28-9 (2S,4aR,8R,8aS)-6-Methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 
• 2873-29-2 D-glucal triacetate 
• 5072-70-8 1-bromo-2,3-dimethyl-2-butene 
• 674769-31-4 Benzoic acid (2S,3S,4R)-2-bromomethyl-4,6-dimethoxy-tetrahydro-pyran-3-yl ester 
• 160400-66-8 methyl 2-deoxy-D-arabinopyranoside 
• 126873-07-2 methyl 3,4,6-tri-O-acetyl-2-deoxy-α/β-D-glucopyranoside 
• 60656-87-3 benzyloxyacetoaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 

Relevant articles and documents

Synthesis of the C(1)-C(12) segment of peloruside A by an α-benzyloxymethyl ketone aldol strategy

The C(1)-C(12) segment of 16-membered antitumor macrolide peloruside A has been prepared by a BF3·OEt2-catalyzed Mukaiyama aldol reaction between a glucose-derived C(1)-C(7) aldehyde and a C(8)-C(12) α-benzyloxymethyl ketone. Exclusive 2,3-anti and moderate 3,5-anti/syn facial selectivity (3.5:1) was observed in the aldol reaction. The key C(1)-C(7) aldehyde contains the required stereochemistry at carbons two, three, and five, and has been efficiently prepared on multigram scales from commercial triacetyl D-glucal.