674782-28-6

Basic information

• Product Name: 4-[4-({1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid
• Synonyms: Benzoic acid, 4-[4-[[1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl]phenoxy]-
• CAS NO: 674782-28-6
• Molecular Formula: C₃₃H₄₃N₃O₆
• Molecular Weight: 577.711
• Mol File: 674782-28-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 800.6°C at 760 mmHg
• Flash Point: 438°C
• Density: 1.29g/cm³
• Vapor Pressure: 4.79E-27mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 4-[4-({1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-({1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid(674782-28-6)
• EPA Substance Registry System: 4-[4-({1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid(674782-28-6)

Safety Data

• Hazardous Substances Data: 674782-28-6(Hazardous Substances Data)

Upstream product

• 2043-61-0 cyclohexanecarbaldehyde 
• 111902-61-5 (2R,3R)-3-cyclohexyl-2,3-epoxypropan-1-ol 
• 42134-55-4 3-cyclohexyl-2-propen-1-ol 
• 4484-35-9 3-cyclohexylacrylic acid 
• 705-95-3 3-cyclohexylacrylic acid methyl ester 
• 80542-16-1 D-threo-2-amino-3-cyclohexyl-3-hydroxypropionic acid 
• 1280013-74-2 C₁₉H₃₃N₃O₃ 
• 2509-18-4 4-(4-formylphenoxy)benzoic acid 
• 1280013-68-4 C₂₆H₃₉N₃O₃ 
• 80542-17-2 (2R,3S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-3-hydroxypropanoic acid 
• 115362-12-4 (-)-(2S,3S)-2,3-epoxy-3-cyclohexyl-1-propanol 
• 1319734-52-5 (4S,5R)-3-benzyl-5-cyclohexyl-2-oxo-oxazolidine-4-carboxylic acid 
• 1280013-87-7 methyl (4R,5R)-3-benzyl-5-cyclohexyl-2-oxo-oxazolidine-4-carboxylate 
• 1280013-86-6 (4R,5R)-3-benzyl-5-cyclohexyl-2-oxo-oxazolidine-4-carboxylic acid 

Downstream Products

• 1428446-03-0 C₅₆H₇₅N₁₁O₁₂ 

Relevant articles and documents

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Following the discovery that hydroxylated derivative 3 (Fig. 1) was one of the oxidative metabolites of the original lead 1, it was found that hydroxylated compound 4 possesses higher in vitro anti-HIV potency than the corresponding non-hydroxylated compo