67496-96-2

Basic information

• Product Name: 3-(aminomethyl)adamantan-1-ol
• Synonyms: 3-(aminomethyl)adamantan-1-ol;3-(Aminomethyl)-1-adamantanol;3-(aminomethyl)adamantan-1-ol hydrochloride;CBDivE_009655;Oprea1_476755;Tricyclo[3,3,1,1(3,7)]decane, 1-ol-3-aminomethyl-
• CAS NO: 67496-96-2
• Molecular Formula: C₁₁H₁₉NO
• Molecular Weight: 181.27466
• Mol File: 67496-96-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 289.1±13.0 °C(Predicted)
• Appearance: /
• Density: 1.202±0.06 g/cm3(Predicted)
• PKA: 15.21±0.40(Predicted)
• CAS DataBase Reference: 3-(aminomethyl)adamantan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(aminomethyl)adamantan-1-ol(67496-96-2)
• EPA Substance Registry System: 3-(aminomethyl)adamantan-1-ol(67496-96-2)

Safety Data

• Hazardous Substances Data: 67496-96-2(Hazardous Substances Data)

Upstream product

• 17768-41-1 adamantylmethylamine 
• 1501-98-0 1-adamantylmethylamine hydrochloride 
• 61040-00-4 1-bromo-3-(aminomethyl)adamantane 

Downstream Products

• 400749-85-1 1-(3,4-xylyl)-3-aminomethyladamantane 
• 136611-70-6 1-(3-sulfo-4-hydroxyphenyl)-3-aminomethyladamantane 
• 142230-21-5 N-(3-{5-[(1Z,4Z,9Z,15Z)-15-{3-[3-(Acetylamino-methyl)-adamantan-1-yl]-4-methoxy-phenyl}-10,20-bis-(4-methoxy-phenyl)-porphyrin-5-yl]-2-methoxy-phenyl}-adamantan-1-ylmethyl)-acetamide 
• 136611-71-7 1-(4-tolyl)-3-aminomethyladamantane methanesulfonate 
• 136611-69-3 1-(4-sulfophenyl)-3-aminomethyladamantane 
• 142230-14-6 C-(3-{2-Methoxy-5-[(5Z,10Z,14Z,19Z)-10,15,20-tris-(4-methoxy-phenyl)-porphyrin-5-yl]-phenyl}-adamantan-1-yl)-methylamine 
• 142230-15-7 C-(3-{5-[(1Z,4Z,9Z,15Z)-15-[3-(3-Aminomethyl-adamantan-1-yl)-4-methoxy-phenyl]-10,20-bis-(4-methoxy-phenyl)-porphyrin-5-yl]-2-methoxy-phenyl}-adamantan-1-yl)-methylamine 
• 142230-17-9 C-{3-[4-((5Z,10Z,14Z,19Z)-10,15,20-Triphenyl-porphyrin-5-yl)-phenyl]-adamantan-1-yl}-methylamine 
• 136611-67-1 1-(3,4-dichlorophenyl)-3-aminomethyladamantane hydrosulfate 

Relevant articles and documents

8-Azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists

The invention provides novel 8-azabicyclo[3.2.1]octane compounds of formula (I): wherein R1, R2, R3, A, and G are defined in the specification, or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.

SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME 1-HYDROXY-3-AMINOALKYLADAMANTANES AND THEIR DERIVATIVES

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