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Eupatolide, a sesquiterpene lactone compound, is derived from the plant species of the genus Eupatorium. It is renowned for its potent anti-inflammatory and anti-cancer properties, traditionally utilized in Asian medicine for treating a variety of inflammatory and immunological disorders. Eupatolide's anti-inflammatory action is attributed to its ability to inhibit the production of pro-inflammatory cytokines and the activation of nuclear factor kappa B (NF-κB), a pivotal regulator of inflammation. Furthermore, it has demonstrated the capacity to induce apoptosis in cancer cells, positioning it as a prospective candidate for the development of innovative anti-cancer drugs. In essence, eupatolide is a bioactive compound with significant therapeutic potential for the management of inflammation and cancer.

6750-25-0

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6750-25-0 Usage

Uses

Used in Pharmaceutical Industry:
Eupatolide is used as an anti-inflammatory agent for its ability to inhibit the production of pro-inflammatory cytokines and the activation of NF-κB, thereby reducing inflammation in various conditions.
Used in Oncology:
Eupatolide is used as an anti-cancer agent for its capacity to induce apoptosis in cancer cells, making it a potential candidate for the development of novel anti-cancer drugs.
Used in Drug Development:
Eupatolide is utilized in the research and development of new pharmaceuticals targeting inflammation and cancer due to its bioactive properties and therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 6750-25-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,5 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6750-25:
(6*6)+(5*7)+(4*5)+(3*0)+(2*2)+(1*5)=100
100 % 10 = 0
So 6750-25-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H20O3/c1-9-5-4-6-10(2)8-13-14(12(16)7-9)11(3)15(17)18-13/h5,8,12-14,16H,3-4,6-7H2,1-2H3/b9-5+,10-8+/t12-,13-,14-/m1/s1

6750-25-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Eupatolide

1.2 Other means of identification

Product number -
Other names (3aR,4R,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-4-hydroxy-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6750-25-0 SDS

6750-25-0Downstream Products

6750-25-0Relevant academic research and scientific papers

DIETHYLAMINE ADDITION TO NATURAL SESQUITERPENIC α-EXOMETHYLENE-γ-LACTONES AND ITS USE FOR CHEMICAL TRANSFORMATIONS OF THESE COMPOUNDS

Harmatha, Juraj,Samek, Zdenek

, p. 2779 - 2785 (2007/10/02)

Addition of diethylamine to exomethylene double bond in natural sesquiterpenic α-methylene-γ-lactones is more advantageous in structural studies than the addition of other amines used so far.In some instances a simultaneous solvolysis of the ester groups also takes place.This fact was made use of for selective deacylation.The possibility of solvolysis impairs the potential use of diethylamine and other amines for the isolations of α-methylene-γ-lactone fractions directly from the extract of natural material.

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