67502-84-5

Basic information

• Product Name: 3H-1,5-Benzodiazepine, 2-(4-nitrophenyl)-4-phenyl-
• CAS NO: 67502-84-5
• Molecular Formula: C21H15N3O2
• Molecular Weight: 341.369
• Mol File: 67502-84-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3H-1,5-Benzodiazepine, 2-(4-nitrophenyl)-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-1,5-Benzodiazepine, 2-(4-nitrophenyl)-4-phenyl-(67502-84-5)
• EPA Substance Registry System: 3H-1,5-Benzodiazepine, 2-(4-nitrophenyl)-4-phenyl-(67502-84-5)

Safety Data

• Hazardous Substances Data: 67502-84-5(Hazardous Substances Data)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 3672-66-0 1-(4-nitrophenyl)-3-phenylprop-2-yn-1-one 
• 5400-95-3 1-(4-nitro-phenyl)-3-phenyl-propane-1,3-dione 

Relevant articles and documents

A sustainable water-tolerant catalyst with enhanced Lewis acidity: Dual activation of Cp2TiCl2 via ligand and solvent

A new strategy was developed to enhance the activity of titanocene dichloride for the synthesis of 2,4-disubstituted-3H-benzo[b]-[1,4]diazepine derivatives by using Cp2TiCl2 as a pre-catalyst. The titanocene was activated in situ in the catalytic system via the coordination with m-phthalic acid and alcohol solvent accompanied with the secession of a cyclopentadienyl ring, leading to the formation of an activated species, [CpTi(OEt)2(η1-C8H5O4)]. In particular, the novel developed half-titanocene catalyst exhibited more superior stability than representative half-titanocene complex, indicated by not only water compatibility for the employment of 30 % aqueous ethanol solution but also the recyclability that the products could be generated without apparent yield decrease after 5 runs. In general, we present a paradigm for sustainable molecular catalysis of titanocene.

3H-1,5-Benzodiazepines from ethynyl ketones and o-phenylenediamines

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