67503-73-5

Usage

Uses

Used in Pharmaceutical Synthesis:
3-acetyl-6-chloroquinolin-4(1H)-one is used as an intermediate in the synthesis of pharmaceutical drugs. Its unique structure and reactivity contribute to the development of new medications with potential therapeutic applications.
Used in Antimicrobial Applications:
In the field of medicine, 3-acetyl-6-chloroquinolin-4(1H)-one is used as an antimicrobial agent for the treatment of bacterial and fungal infections. Its chemical properties allow it to target and eliminate harmful microorganisms, providing a potential solution for combating infections.
Used in Drug Development Research:
3-acetyl-6-chloroquinolin-4(1H)-one is utilized in drug development research to explore its potential biological activities and therapeutic applications. Its synthesis and study contribute to the advancement of pharmaceutical science and the discovery of new treatments for various diseases.
Used in Chemical Bonding Studies:
In the realm of chemistry, 3-acetyl-6-chloroquinolin-4(1H)-one serves as a subject for chemical bonding studies. Its unique structure allows researchers to investigate its reactivity and interactions with other compounds, furthering our understanding of chemical bonding and its implications in various applications.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 106-47-8 4-chloro-aniline 
• 122-51-0 orthoformic acid triethyl ester 
• 5202-89-1 4-chlorobenzenesulfonyl chloride 

Downstream Products

• 865092-81-5 3-acetyl-6-chloro-1-(4-fluorophenyl)methyl-4(1H)-quinolinone 

Relevant academic research and scientific papers

Copper-Catalyzed Aza-Michael Addition of 2-Aminobenzoate to β-Substituted α,β-Unsaturated Ketones: One-Pot Synthesis of 3-Carbonyl-2-Substituted Quinolin-4(1H)-ones

We present a new and straightforward one-pot process for the synthesis of 3-carbonyl-4-quinolone derivatives through highly efficient Cu-catalyzed aza-Michael addition of 2-aminobenzoates to β-substituted α,β-unsaturated ketones/cyclization/mild oxidation

Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: Design, synthesis, and biological activities

Novel quinolinonyl diketo acids were designed to obtain integrase (IN) inhibitors selectively active against the strand transfer (ST) step of the HIV integration process. Those new compounds are characterized by a single aryl diketo acid (DKA) chain in co

QIUNOLIN-4-ONES AS INHIBITORS OF RETROVIRAL INTEGRASE FOR THE TREATMENT OF HIV, AIDS AND AIDS RELATED COMPLEX (ARC)

Novel quinoline inhibitors of retroviral integrase, particularly HIV-1 integrase. The quinoline inhibitors are oxoquinolines of the following formula (I) that can be used for preventing or treating AIDS or HIV infection in a subject. Wherein Z is selected