67508-09-2

Basic information

• Product Name: N-dimethylaminoprostaglandin F2alpha
• Synonyms: N-dimethylaminoprostaglandin F2alpha;(1R,3S,4R,5R)-4-[(Z)-7-(dimethylamino)hept-2-enyl]-5-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentane-1,3-diol
• CAS NO: 67508-09-2
• Molecular Formula: C22H41NO3
• Molecular Weight: 367.56584
• Mol File: 67508-09-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 492.6°C at 760 mmHg
• Flash Point: 218.1°C
• Appearance: /
• Density: 1.041g/cm³
• Vapor Pressure: 9.03E-12mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: N-dimethylaminoprostaglandin F2alpha(CAS DataBase Reference)
• NIST Chemistry Reference: N-dimethylaminoprostaglandin F2alpha(67508-09-2)
• EPA Substance Registry System: N-dimethylaminoprostaglandin F2alpha(67508-09-2)

Safety Data

• Hazardous Substances Data: 67508-09-2(Hazardous Substances Data)

Usage

Description

N-dimethylaminoprostaglandin F2alpha, also known as PGF2α dimethyl amine, is a derivative of PGF2α designed as a prostaglandin antagonist for in vitro and in vivo studies. It is a weak FP receptor antagonist with the ability to inhibit the contractile effects of PGF2α in gerbil colon at a specific dose.

Uses

Used in Pharmaceutical Research:
N-dimethylaminoprostaglandin F2alpha is used as a research compound for studying the effects and mechanisms of prostaglandin antagonists. Its weak FP receptor antagonistic properties make it a valuable tool in understanding the role of prostaglandins in various physiological processes and potential therapeutic applications.
Used in Drug Development:
N-dimethylaminoprostaglandin F2alpha is utilized in the development of new drugs targeting prostaglandin receptors. Its antagonistic activity can be leveraged to create medications that modulate the effects of prostaglandins, potentially leading to treatments for a range of conditions influenced by these bioactive molecules.
Used in In Vitro Studies:
In laboratory settings, N-dimethylaminoprostaglandin F2alpha serves as a key component in in vitro experiments aimed at investigating the interactions between prostaglandins and their receptors. This helps researchers gain insights into the molecular mechanisms underlying the biological actions of prostaglandins.
Used in In Vivo Studies:
N-dimethylaminoprostaglandin F2alpha is also employed in in vivo studies to evaluate the efficacy and safety of prostaglandin antagonists in living organisms. This allows researchers to observe the compound's effects on various physiological parameters and assess its potential as a therapeutic agent.

InChI:InChI=1/C22H41NO3/c1-4-5-9-12-18(24)14-15-20-19(21(25)17-22(20)26)13-10-7-6-8-11-16-23(2)3/h7,10,14-15,18-22,24-26H,4-6,8-9,11-13,16-17H2,1-3H3/b10-7-,15-14+/t18-,19+,20+,21-,22+/m0/s1