67508-30-9

Upstream product

• 462-94-2 1,5-diaminopentane 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 87338-06-5 1,6-bis(p-tolylsulfonyl)-1,6-diazacycloundecane 
• 109950-03-0 N-[2-Methoxy-1-(toluene-4-sulfonyl)-piperidin-3-yl]-4-methyl-benzenesulfonamide 
• 87338-07-6 1,7-bis(p-tolylsulphonyl)-1,7-diazacyclododecane 
• 120808-64-2 1,7-bis(p-tolylsulphonyl)-1,7-diazacyclopentadecane 
• 87338-13-4 1,10-bis(p-tolylsulfonyl)-1,10-diaza-4,7-dioxacyclopentadecane 
• 87338-14-5 1,13-bis(p-tolylsulfonyl)-1,13-diaza-4,7,10-trioxacyclooctadecane 
• 80958-64-1 N²,N⁸-di-p-toluenesulfonyl-14-hydroxy-15-hydroxymethyl-14,15'-O-isopropylidene-2,8-diaza<9>(2,5)pyridinophane 
• 84944-16-1 N²,N⁸-Di-p-tosyl-14-hydroxy-15-hydroxymethyl-14,15'-O-isopropylidene-11-methyl-2,8-diaza<9>(2,5)pyridinophane 
• 80958-58-3 C₁₉H₂₄N₂O₄S₂^(2-)*2Na⁽¹⁺⁾ 
• 87338-08-7 1,7-bis(p-tolylsulfonyl)-1,7-diazacycloheptadecane 
• 73276-85-4 N,N'-bis(2-hydroxyethyl)-N,N'-ditosylpentamethylene diamine 
• 97530-93-3 1,3-ditosylperhydro-1,3-diazecine 
• 277760-35-7 N₁,N₅-di(p-toluenesulfonyl)-1,5-di(ethylamino)pentane 
• 278807-16-2 C₂₉H₄₄N₄O₆S₂ 

Relevant academic research and scientific papers

Transition-Metal-Free One-Step Synthesis of Ynamides

A robust transition-metal-free one-step strategy for the synthesis of ynamides from sulfonamides and (Z)-1,2-dichloroalkenes or alkynyl chlorides is presented. This method is not only effective for internal ynamides but also amenable for terminal ynamides. Various functional groups, even the vinyl moiety, are compatible, and thus, this strategy offers the opportunity for further functionalization.

MACROHETEROCYCES. XXXVI. A CONVENIENT METHOD FOR SYNTHESIS OF DI- AND POLYAZACROWN ETHERS

A method is proposed for the production of di- and polyazacrown ethers by the condensation of bissulfonamides with dibromides or ditosyloxy derivatives in a two-phase aqueous alkali-toluene (benzene) system.The optimum concentration range for the substrate and the alkylating agent is 0.017-0.1 M.The catalytic activity of the quaternary ammonium salts decreases in the order (Bu)4NI > (Bu4)NBr > (Bu4)NCl > (Bu4)NHSO4 > (C2H5)3C6H5CH2NCl >> (Et)4NI > (Et)4NBr.The highest yields of te 12-membered azacrown ethers are obtained in the presence of lithium hyroxide, and the largest yields of the crown ethers with larger ring sizes are obtained in the presence of sodium or potassium hydroxide, and this is probably due to the matrix effects of the cation.

Preferential Introduction of a Pyridylmethyl Group into Sulfonamides as an Approach to an Intramolecular Transimination

N,N'-Bis(p-tolylsulfonyl)-α,ω-alkanediamine disodium salts (n=3, 4, 5, 6, 7, 8, 9, 10) were subjected to monopyridylmethylation by the reaction with 5'-deoxy-5'-chloro- or 5'-deoxy-2'-chloro-3,4'-O-isopropylidenepyridoxine hydrochloride, accompanied by th