675103-20-5

Upstream product

• 10265-98-2 (4-chloro-3-nitro-phenyl)-phenyl ether 
• 3218-02-8 cyclohexylmethylamine 
• 98-80-6 phenylboronic acid 
• 610-78-6 3-nitro-4-chlorophenol 

Downstream Products

• 675103-21-6 N₁-cyclohexylmethyl-4-phenoxy-benzene-1,2-diamine 

Relevant academic research and scientific papers

Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase

A new class of benzimidazolone p38 MAP kinase inhibitors was discovered through high-throughput screening. X-ray crystallographic data of the lead molecule with p38 were used to design analogues with improved binding affinity and potency in a cell assay o

BENZIMIDAZOLONES AND THEIR USE AS CYTOKINE INHIBITORS

Disclosed are benzimidazolone compounds of formulas (II) wherein X is O, S or NR5. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammatio