675111-88-3 Usage
Uses
Used in Scientific Research and Development:
4-Chloro-1-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid is used as a research compound for the investigation of its chemical properties, potential applications, and interactions with other compounds. Its synthesis and study contribute to the understanding of pyrazolopyridine derivatives and their possible uses in various fields.
Used in Pharmaceutical Development:
Although specific applications are not readily available, 4-Chloro-1-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid may be used as a starting material or intermediate in the development of new pharmaceutical compounds. Its unique structure and potential reactivity could be explored for the creation of novel drug candidates, particularly in the fields of medicinal chemistry and drug discovery.
Used in Chemical Synthesis:
4-Chloro-1-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid can be used as a building block in the synthesis of more complex organic molecules. Its presence in the molecular structure may impart specific properties or reactivity that could be exploited in the creation of new compounds with desired characteristics, such as improved stability, solubility, or biological activity.
Used in Material Science:
4-Chloro-1-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid may also find applications in material science, where its unique structure and properties could be utilized in the development of new materials with specific characteristics. This could include applications in areas such as polymer chemistry, where the compound could be incorporated into the design of new polymers with tailored properties for use in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 675111-88-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,5,1,1 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 675111-88:
(8*6)+(7*7)+(6*5)+(5*1)+(4*1)+(3*1)+(2*8)+(1*8)=163
163 % 10 = 3
So 675111-88-3 is a valid CAS Registry Number.
675111-88-3Relevant academic research and scientific papers
Discovery of new orally active phosphodiesterase (PDE4) inhibitors
Ochiai, Hiroshi,Ishida, Akiharu,Ohtani, Tazumi,Kusumi, Kensuke,Kishikawa, Katuya,Yamamoto, Susumu,Takeda, Hiroshi,Obata, Takaaki,Nakai, Hisao,Toda, Masaaki
, p. 1098 - 1104 (2007/10/03)
A series of 4-anilinopyrazolopyridine derivatives were synthesized and biologically evaluated as inhibitors of phosphodiesterase (PDE4). Chemical modification of 3, a structurally new chemical lead that was found in our in-house library, was focused on 1- and 3-substituents. Full details of the discovery of a new orally active chemical lead 5 are presented. Structure-activity relationship data, pharmacological evaluation, and the subtype selectivity study are also presented.
PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
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Page 99, (2008/06/13)
The invention relates to a compound of formula (I) or a salt thereof: wherein:R1 is C1-4alkyl, C1-3fluoroalkyl, -CH2CH2OH or -CH2CH2CO2C1-2alkyl;R2 is a hydrogen atom (H), methyl or C1fluoroalkyl;R3 is optionally substituted C3-8cycloalkyl or optionally substituted mono-unsaturated-C5-7cycloalkenyl or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc); in which n1 and n2 independently are 1 or 2; and in which Y is O, S, SO2, or NR10; or R3 is a bicyclic group (dd) or (ee): ; and wherein X is NR4R5 or OR5a. The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.
