675128-77-5

Upstream product

• 1352406-16-6 C₂₁H₂₄O₅ 
• 160400-66-8 methyl 2-deoxy-D-arabinopyranoside 
• 6752-48-3 methyl 4,6-O-benzylidene-2-deoxy-α,β-D-arabino-hexopyranoside 
• 61-58-5 2-deoxy-D-arabino-hexopyranose 
• 675128-75-3 (2R,3S,4R)-6-Methoxy-2-trityloxymethyl-tetrahydro-pyran-3,4-diol 
• 675128-76-4 (2R,3S,4R)-3,4-Bis-benzyloxy-6-methoxy-2-trityloxymethyl-tetrahydro-pyran 

Downstream Products

• 725268-38-2 (2S,3R)-2,3-Bis-benzyloxy-5-hydroxy-cyclohexanone 
• 189758-78-9 GS 416 
• 614752-30-6 (2S,3S,4R,6S)-3,4-Bis-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde 

Relevant academic research and scientific papers

Chiral pool synthesis of calystegine A3 from 2-deoxyglucose via a Brown allylation

Calystegine A3 is a naturally occurring nortropane iminosugar of which there previously have been three total syntheses. Inspired by our previous work we here report on a fourth approach using 17 steps from 2-deoxy-d-glucose applying a diastereoselective allylation protocol.

Synthetic studies on antascomicin A: Construction of the C18-C34 fragment

Stereoselective synthesis of the C18-C34 fragment of antascomicin A is described. Construction of the C27-C34 carbocycle moiety was achieved via catalytic Ferrier carbocylization and Johnson-Claisen rearrangement, which was converted to iodide 2 by use of