67515-75-7

Upstream product

• 67536-83-8 methyl 5-<(3-chlorobenzylidene)amino>-2-pyridinecarboxylate 
• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 67536-82-7 5-[(3-chloro-benzyl)-methyl-amino]-pyridine-2-carboxylic acid 
• 67516-36-3 5-[(3-Chloro-benzyl)-methyl-amino]-pyridine-2-carboxylic acid methyl ester 
• 67515-77-9 sodium 5-(m-chlorobenzylamino)-pyridine-2-carboxylate 

Relevant academic research and scientific papers

Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids

5-Amino-2-pyridinecarboxylic acids, e.g. those of the formula STR1 R=H, phenyl unsubst. or subst. by alkyl, alkoxy, halo, CF3, Cn, CONH2 or phenoxy R'=H, alkyl or aralkyl m=1-4 or functional derivatives thereof, are hypotensive agent

Synthesis and antihypertensive activity of 5-amino-2-pyridinecarboxylic acid derivatives

The synthesis of various substituted 5-amino-2-pyridinecarboxylic acids and their derivatives is described by three general methods: reductive alkylation of methyl-5-amino-2-pyridinecarboxylates (2) and subsequent hydrolysis; alkylation of the urethane (9