67515-91-7Relevant academic research and scientific papers
Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids
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, (2008/06/13)
5-Amino-2-pyridinecarboxylic acids, e.g. those of the formula STR1 R=H, phenyl unsubst. or subst. by alkyl, alkoxy, halo, CF3, Cn, CONH2 or phenoxy R'=H, alkyl or aralkyl m=1-4 or functional derivatives thereof, are hypotensive agent
Synthesis and antihypertensive activity of 5-amino-2-pyridinecarboxylic acid derivatives
Finch,Campbell,Gemenden,Povalski
, p. 1405 - 1410 (2007/10/02)
The synthesis of various substituted 5-amino-2-pyridinecarboxylic acids and their derivatives is described by three general methods: reductive alkylation of methyl-5-amino-2-pyridinecarboxylates (2) and subsequent hydrolysis; alkylation of the urethane (9
