6752-19-8Relevant academic research and scientific papers
Facile Construction of Hydantoin Scaffolds via a Post-Ugi Cascade Reaction
Xu, Zhi-Gang,Ding, Yong,Meng, Jiang-Ping,Tang, Dian-Yong,Li, Yong,Lei, Jie,Xu, Chuan,Chen, Zhong-Zhu
, p. 2199 - 2202 (2018)
A small series of hydantoins was efficiently synthesized via a two-step Ugi/cyclization reaction sequence using alkyne group as a leaving group under basic conditions. This microwave-assisted one-pot cyclization strategy could be applicable to other multicomponent reactions (MCRs) for synthesizing bioactive and drug-like hydantoins.
