67525-95-5Relevant academic research and scientific papers
Ascorbic Acid Promoted Metal-Free Synthesis of Aryl Sulfides with Anilines Nitrosated in Situ by tert -Butyl Nitrite
Bu, Mei-Jie,Lu, Guo-Ping,Cai, Chun
supporting information, p. 1841 - 1846 (2015/08/06)
A mild, metal-free synthesis of aryl sulfides has been disclosed. Aryl diazonium ion was generated by the in situ nitrosation of aniline, and it was reduced by ascorbic acid (vitamin C) to form aryl radical, which underwent a thiolation with disulfide to yield aryl sulfide. The reaction proceeded smoothly without heating or irradiation. This strategy was also expanded to the synthesis of aryl selenides.
Regioselective synthesis of methyl 3-thiothiophene-2-carboxylate derivatives utilizing a dehydration-type ti-dieckmann condensation
Nagase, Ryohei,Gotoh, Hideki,Katayama, Mayumi,Manta, Naoki,Tanabe, Yoo
, p. 697 - 708 (2008/03/13)
Regioselective dehydration-type Ti-Dieckmann condensation of 3-(methoxycarbonylmethylthio)propanethioates successfully afforded methyl thiophene-2-carboxylates and methyl 4,5-dihydrothiophene-2-carboxylates, utilizing TiCl4 - Et3N an
Aromatization of Dihydrothiophenes. Thiophenesaccharin: A Sweet Surprise
Rossy, Phillip A.,Hoffmann, Werner,Mueller, Norbert
, p. 617 - 620 (2007/10/02)
Sulfuryl chloride has been shown to be highly effective in the dehydrogenation of 3,4-disubstituted-2,5-dihydrothiophenes and 2,3-disubstituted-4,5-dihydrothiophenes, in which the 3,4 and 2,3 substitutents are part of a β-keto carbonyl functionality or it
Thiophene compounds and their manufacture
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, (2008/06/13)
New thiophene compounds and a new process for the manufacture of thiophene compounds by dehydrogenating dihydrothiophene with certain halogen compounds. The products are starting materials for the manufacture of pharmaceuticals, dyes and plant protection agents and, in particular, for the manufacture of additives to foodstuffs, feeds, beverages and pharmaceuticals.
