67528-33-0Relevant academic research and scientific papers
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4α-phorbol esters: A structure-activity study
Klausen, Thomas Kj?r,Pagani, Alberto,Minassi, Alberto,Ech-Chahad, Abdellah,Prenen, Jean,Owsianik, Grzegorz,Hoffmann, Else Kay,Pedersen, Stine Falsig,Appendino, Giovanni,Nilius, Bernd
, p. 2933 - 2939 (2009)
The mechanism of activation of the transient receptor potential vanilloid 4 (TRPV4) channel by 4α-phorbol esters was investigated by combining information from chemical modification of 4α-phorbol-didecanoate (4α-PDD, 2a), site-directed mutagenesis, Casup
