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1-methyl-5-phenyl-1,2,3,6-tetrahydropyridine, also known as MPTP, is a synthetic chemical compound with the molecular formula C12H17N. It was first synthesized in the 1970s as a potential treatment for opioid addiction. However, it gained notoriety when it was discovered that it could cause severe and irreversible Parkinson's-like symptoms in humans, leading to its classification as a neurotoxin. MPTP is structurally similar to the neurotransmitter dopamine and can cross the blood-brain barrier, where it is metabolized into a toxic compound that selectively destroys dopaminergic neurons in the substantia nigra, a region of the brain involved in movement control. This discovery has contributed significantly to the understanding of Parkinson's disease and the development of potential treatments, as researchers use MPTP-induced animal models to study the disease and test new therapies.

6755-56-2

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6755-56-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6755-56-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,5 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6755-56:
(6*6)+(5*7)+(4*5)+(3*5)+(2*5)+(1*6)=122
122 % 10 = 2
So 6755-56-2 is a valid CAS Registry Number.

6755-56-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-methyl-5-phenyl-3,6-dihydro-2H-pyridine

1.2 Other means of identification

Product number -
Other names 1,2,3,6-Tetrahydropyridine,1-methyl-5-phenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6755-56-2 SDS

6755-56-2Downstream Products

6755-56-2Relevant academic research and scientific papers

Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water

Li, Tiejun,Peng, Henian,Tang, Wenjun,Tian, Duanshuai,Xu, Guangqing,Yang, He

, p. 4327 - 4337 (2021/05/31)

A series of unsaturated carbonyls, quinones, and pyridinium salts have been effectively reduced to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields with tetrahydroxydiboron/water as a mild, convenient, and metal-free reduction system. Deuterium-labeling experiments have revealed this protocol to be an exclusive transfer hydrogenation process from water. This journal is

REDUCTION OF PHENYL-SUBSTITUTED PYRIDINIUM METHOIODIDES WITH SODIUM BOROHYDRIDE. FORMATION OF AMINE-BORANE COMPLEXES IN WATER.

Gessner, Wieslaw,Brossi, Arnold

, p. 911 - 916 (2007/10/02)

Reduction of phenyl-substituted pyridinium methoiodides with sodium borohydride in water afforded besides the desired tetrahydropyridines substantial amounts of amine-borane complexes.Reduction in methanol afforded tetrahydropyridines in high yield, with almost no amine-boranes formed.

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