67589-90-6

Upstream product

• 38289-29-1 4-trans-pentylcyclohexane-1-carboxylic acid 
• 26311-45-5 4-pentylbenzoic acid 

Downstream Products

• 73255-66-0 4-Pentyl-cyclohexanecarboxylic acid 4-cyano-cyclohexyl ester 
• 80522-15-2 2-(trans-4-Pentyl-2-cyclohexyl)-6-(trans-4-pentylcyclohexanoyloxy)-4H-3,1-benzoxazin-4-one 
• 70997-06-7 4-Cyanophenyl-2-chloro-4-(trans-4-pentylcyclohexylcarbonyloxy)-benzoat 
• 104582-79-8 4-Pentyl-cyclohexanecarboxylic acid 4'-cyano-3'-methyl-biphenyl-4-yl ester 
• 139564-62-8 trans-trans-3,11-Bis(trans-4-pentylcyclohexanoyl)dispiro<5.1.5.2>pentadecan-7-on 
• 139629-03-1 cis-trans-3,11-Bis(trans-4-pentylcyclohexanoyl)dispiro<5.1.5.2>pentadecan-7-on 
• 345318-01-6 1-(4-Pentyl-cyclohexyl)-2-(4-propyl-phenyl)-ethanone 
• 345322-08-9 2-(4-Butyl-phenyl)-1-(4-pentyl-cyclohexyl)-ethanone 
• 345321-89-3 1-(4-Pentyl-cyclohexyl)-2-(4-propoxy-phenyl)-ethanone 
• 67589-72-4 4-pentylphenyl trans-4'-pentylcyclohexanecarboxylate 

Relevant academic research and scientific papers

Palladium-Catalyzed Migratory Insertion of Carbenes and C-C Cleavage of Cycloalkanecarboxamides

A palladium catalyzed reaction of cycloalkanecarboxamides and diazomalonates or bis(phenylsulfonyl)diazomethane has been developed. The reaction proceeds via carbene migratory insertion and cascade C-C cleavage pathways. Cycloalkanecarboxamides with four to seven membered rings are applicable in the transformation. A series of ring opening products were prepared with moderate yields. The finding provides valuable clues for the development of new reactions involving carbene migratory insertion and the cleavage of unstrained C(sp3)-C(sp3) bonds.

COMPOUND HAVING A TRIPTYCENE MOIETY

A compound having a triptycene moiety represented by formula (1) is disclosed. In the formula, A1 and A2 represent —S—, —O—, —CO—, or —NR—; R1 and R3 represent a substituent; n is an integer from 0 to 2; R4

CHOLESTERIC LIQUID CRYSTAL COMPOSITION

A cholesteric liquid crystal composition containing at least one esterified product selected from the group consisting of (1) an esterified product of a hydrolysate of (A) a γ-oryzanol and (B1) a carboxylic acid compound, (2) an esterified product of a hy

Improved synthesis of trans-4-alkylcyclohexane carboxylic acids

Several stereomerically pure amino acid derivatives containing the N-terminal trans-4-alkylcyclohexanoyl fragment were obtained. Hydrogenation of 4-alkylbenzoic acids in the presence of a special Ru-Ni/C catalytic system and isomerization of the resulting mixture of trans- and cis-isomers of 4-alkylcyclohexanecarboxylic acids were used as the key steps. The stereomeric configuration of all compounds was confirmed by 1H NMR spectroscopy. The compounds obtained possess a broad biological activity potential and are useful intermediates in the synthesis of stereomerically pure modified peptides.

Synthesis of plasmepsin II inhibitors - Potential antimalarial agents

A new series of plasmepsin II (PM II) inhibitors has been prepared based on 4-aminopiperidine-tert-butyl-carbamate (1). These compounds might be useful as antimalarial drugs acting via a new mechanism, and therefore be less susceptible to parasite resista

Rod-Like Dispiro Compounds

A number of symmetrically and unsymmetrically substituted spiro compounds were synthesized starting from the dispirotrione 1. The trans-trans isomers of 2, 3, 6-10, and 11 were separated from the cis-cis and cis-trans isomers.From the trispiro co

Long-acting androgenic compounds and pharmaceutical compositions thereof

Long-acting androgenic compositions comprising C 4 -C 6 cycloalkyl carboxylic acids of testosterone and a pharmaceutically acceptable carrier medium. The ester can be dissolved in an acceptable oily medium or suspended in an aqueous medium in the form of

Synthesis and Liquid Crystalline Phases of Pyridazine Derivatives II

Four more pyridazine compounds were synthesized.The compounds have a general structure R-X-Y-Z-R'; where Y is 3,6 disubstituted pyridazine ring, X and Z are either trans cyclohexyl or phenyl rings, R and R' are n-alkyl groups.The structure assignments were confirmed by carbon 13 NMR.Their liquid crystalline properties were evaluated.When both X and Z are cyclohexyl rings, the compounds have a single smectic b phase.However, if a phenyl ring is introduced into the system, the morphology becomes complicated.Keywords: synthesis, pyridazine, smectic, classification

Synthesis and Physical Properties of Alkoxymethylene Substituted Phenyl Cyclohexanecarboxylates

The homologous series of 4-alkoxymethylene-substituted-phenyl 4'-alkylcyclohexanecarboxylates are prepared.And their transition temperatures, bulk viscosities and birefringences have been measured comparing with the series of 4-alkoxy-substituted-phenyl 4'-alkylcyclohexanecarboxylates.The differences between the alkoxymethylene-substituted series and alkoxy-substituted series are discussed.Alkoxymethylene groups contribute to lowering the transition temperatures, and also reducing the bulk viscosities and optical anisotropy compared to the alkoxy groups as terminal groups of mesogens.This is apparently due to the higher flexibility of the alkoxymethylene groups, which affected the packing of molecules.

1-(TRANS-4 prime -N-ALKYLCYCLOHEXYL)-2-(4 double prime -CYANOPHENYL)ETHANES - A NEW SERIES OF STABLE NEMATOGENS OF POSITIVE DIELECTRIC ANISOTROPY.

The synthesis and some important properties of the 1-(trans-4 prime -n-alkylcyclohexyl)-2-(4 double prime -cyanophenyl)ethanes - where n-alkyl equals C//1 to C//7 - are described.