676-77-7Relevant articles and documents
Minato et al.
, p. 103,108 (1977)
Synthesis of high specific activity [14CO] methyl isocyanate and its use in the preparation of [14CO] eserine, [14CO] carbaryl and [14CO] IPMU
Poullain,Noel
, p. 387 - 398 (2007/10/03)
The preparation of [14CO] methyl isocyanate from [1-14C] acetyl chloride and activated sodium azide through the Curtius rearrangement was optimized (50% yield/[1-14C] sodium acetate- 50 mCi/mmol) and the reagent immediately used for the synthesis of [14CO] eserine, [14CO] carbaryl and [14CO] IPMU. The condensation of methyl isocyanate with eseroline in the presence of triethylamine does not give rise to eserine but to the isomeric urea derivative 3.