676-84-6 Usage
Uses
Trimethylsulfonium Chloride is used as a reagent in the preparation of spirastrellolide A Me ester via Suzuki coupling, Yamaguchi lactonization, Julia-Kocienski olefination, bond cleavage, and ozonolysis, its antitumor activity, and SAR with truncated variants.
Definition
ChEBI: A sulfonium compound in which the substituents on sulfur are three methyl groups. It is found in the midgut gland of the sea hare, Aplysia brasiliana, and exhibits probable ability to inhibit cholinergic responses.
Check Digit Verification of cas no
The CAS Registry Mumber 676-84-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 6 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 676-84:
(5*6)+(4*7)+(3*6)+(2*8)+(1*4)=96
96 % 10 = 6
So 676-84-6 is a valid CAS Registry Number.
InChI:InChI=1/C3H9S.NO3/c1-4(2)3;2-1(3)4/h1-3H3;/q+1;-1
676-84-6Relevant articles and documents
Sunlight-driven trifluoromethylation of olefinic substrates by photoredox catalysis: A green organic process
Akita, Munetaka,Koike, Takashi
, p. 742 - 751 (2015/07/15)
The principles and utility of photoredox catalysis in organic synthesis are described. After a brief description of the features of the two types of catalytic photoredox processes following the reductive quenching cycle (RQC) and the oxidative quenching cycle (OQC), the discussion is focused on organic transformations based on OQC, in particular the trifluoromethylation of olefinic substrates with electrophilic trifluoromethylating reagents furnishing solvolytic addition products and substitution products. It is concluded that catalytic photoredox systems are green from the point of view of harmfulness, safety, and energy source (visible light, including sunlight). Future prospects of photoredox catalysis will be also discussed.
