6760-14-1

Usage

Chemical Properties

Off-white solid

InChI:InChI=1/C6H5N3O4/c7-5-4(6(10)11)1-3(2-8-5)9(12)13/h1-2H,(H2,7,8)(H,10,11)

Upstream product

• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 98139-19-6 2-nitraminonicotinic acid 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 

Downstream Products

• 4214-76-0 5-nitro-pyridin-2-ylamine 
• 6854-07-5 2-hydroxy-5-nitropyridine-3-carboxylic acid 
• 1071465-78-5 2-amino-N-(3,4-dichlorobenzyl)-5-nitronicotinamide 
• 1071465-82-1 benzyl 3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-6-ylcarbamate 
• 1071465-83-2 2-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-6-ylamino)-2-oxoethyl acetate 
• 1071465-56-9 N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-6-yl)-2-hydroxyacetamide 
• 1071465-79-6 3-(3,4-dichlorobenzyl)-6-nitropyrido[2,3-d]pyrimidin-4(3H)-one 
• 1071465-81-0 6-amino-3-(3,4-dichlorobenzyl)pyrido[2,3-d]pyrimidin-4(3H)-one 

Relevant academic research and scientific papers

N- (6-AMINOPYRIDIN-3-YL) -3- (SULFONAMIDO) BENZAMIDE DERIVATIVES AS B-RAF INHIBITORS FOR THE TREATMENT OF CANCER

Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

SYNTHESES WITH AROMATIC NITRAMINES, VI SUBSTITUENT EFFECT IN THE PHOTOLYTIC REARRANGEMENT OF NITRAMINOPYRIDINES

All isomeric ring-substituted methyl-2-nitraminopyridines, both 3-nitro- and 5-nitro-2-nitraminopyridines, 5-chloro- and 3-carboxy-2-nitraminopyridines, as well as 3,5-dibromo-2-nitraminopyridine were photolyzed in methanol by irradiation with a low-pressure mercury lamp (253.7 nm).Preference was generally noted for the migration of the side-chain nitro group to the vicinal β-position. 3,5-Dibromo-2-nitraminopyridine gave both 2-amino-3,5-dibromopyridine and 3,5-dibromopyridine-2-one.The ratio of the preparative and quantum yields of the two products were 2.5 and 3.0, respectively.