676133-18-9Relevant academic research and scientific papers
Thiazoles and thiopyridines: Novel series of high affinity h5HT 7 ligands
Thomson, Christopher G.,Beer, Margaret S.,Curtis, Neil R.,Diggle, Helen J.,Handford, Emma,Kulagowski, Janusz J.
, p. 677 - 680 (2007/10/03)
A series of thiazole based 5HT7 ligands has been identified from screening. Optimisation of the pendent aryl group and modification of the core gave a related series of high affinity, selective thiopyridine based 5HT7 ligands, the most active of which behaves as a partial agonist.
