676133-70-3

Basic information

• Product Name: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[[(4S)-3,4-dihydro-6-iodo-2H- 1-benzopyran-4-yl]amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester
• CAS NO: 676133-70-3
• Molecular Formula: C24H29F2IN2O4
• Molecular Weight: 574.407
• Mol File: 676133-70-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[[(4S)-3,4-dihydro-6-iodo-2H- 1-benzopyran-4-yl]amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[[(4S)-3,4-dihydro-6-iodo-2H- 1-benzopyran-4-yl]amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(676133-70-3)
• EPA Substance Registry System: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[[(4S)-3,4-dihydro-6-iodo-2H- 1-benzopyran-4-yl]amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(676133-70-3)

Safety Data

• Hazardous Substances Data: 676133-70-3(Hazardous Substances Data)

Downstream Products

• 676134-13-7 tert-butyl (1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-{[(4S)-6-neopentyl-3,4-dihydro-2H-chromen-4-yl]amino}propylcarbamate 
• 676133-71-4 N-((1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-{[(4S)-6-isobutyl-3,4-dihydro-2H-chromen-4-yl]amino}propyl)acetamide hydrochloride 

Relevant articles and documents

2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES

Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s disease and other diseases characterized by deposition of A beta peptide in a mammal.