Cas 676136-48-4,Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[(6-ethyl-1,2,3,4-tetrahydro-1- methyl-4-quinolinyl)amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester

676136-48-4

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Basic information

Product Name: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[(6-ethyl-1,2,3,4-tetrahydro-1- methyl-4-quinolinyl)amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester
Synonyms:
CAS NO:676136-48-4
Molecular Formula: C27H37F2N3O3
Molecular Weight: 489.606
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[(6-ethyl-1,2,3,4-tetrahydro-1- methyl-4-quinolinyl)amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[(6-ethyl-1,2,3,4-tetrahydro-1- methyl-4-quinolinyl)amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(676136-48-4)
EPA Substance Registry System: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-3-[(6-ethyl-1,2,3,4-tetrahydro-1- methyl-4-quinolinyl)amino]-2-hydroxypropyl]-, 1,1-dimethylethyl ester(676136-48-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 676136-48-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 676136-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,6,1,3 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 676136-48:
(8*6)+(7*7)+(6*6)+(5*1)+(4*3)+(3*6)+(2*4)+(1*8)=184
184 % 10 = 4
So 676136-48-4 is a valid CAS Registry Number.

676136-48-4Upstream product

676136-48-4Downstream Products

676136-49-5 (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(6-ethyl-1-methyl-1,2,3,4-tetrahydroquinolin-4-yl)amino]butan-2-ol

676136-48-4Relevant academic research and scientific papers

2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES

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Page/Page column 244-245, (2008/06/13)

Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s disease and other diseases characterized by deposition of A beta peptide in a mammal.

METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS

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Page/Page column 108; 111-112, (2010/02/14)

The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

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